Next‐generation sequencing: ready for the clinics?
AN Desai, A Jere - Clinical genetics, 2012 - Wiley Online Library
Desai AN, Jere A. Next‐generation sequencing: ready for the clinics? Next‐generation
sequencing (NGS) has transformed genomic research by decreasing the cost of sequencing and …
sequencing (NGS) has transformed genomic research by decreasing the cost of sequencing and …
Metal–organic frameworks: functional luminescent and photonic materials for sensing applications
Metal–organic frameworks (MOFs) or porous coordination polymers (PCPs) are open,
crystalline supramolecular coordination architectures with porous facets. These chemically …
crystalline supramolecular coordination architectures with porous facets. These chemically …
[HTML][HTML] CTLA-4 and PD-1 pathways: similarities, differences, and implications of their inhibition
EI Buchbinder, A Desai - American journal of clinical oncology, 2016 - journals.lww.com
The cytotoxic T-lymphocyte–associated antigen 4 (CTLA-4) and programmed death 1 (PD-1)
immune checkpoints are negative regulators of T-cell immune function. Inhibition of these …
immune checkpoints are negative regulators of T-cell immune function. Inhibition of these …
Compassionate use of tecovirimat for the treatment of monkeypox infection
AN Desai, GR Thompson, SM Neumeister… - Jama, 2022 - jamanetwork.com
Methods| Patients were eligible for tecovirimat treatment following laboratory confirmation of
orthopoxvirus infection from skin lesions by polymerase chain reaction. Outpatients referred …
orthopoxvirus infection from skin lesions by polymerase chain reaction. Outpatients referred …
[HTML][HTML] Dapagliflozin in heart failure with mildly reduced or preserved ejection fraction
Background Sodium–glucose cotransporter 2 (SGLT2) inhibitors reduce the risk of hospitalization
for heart failure and cardiovascular death among patients with chronic heart failure …
for heart failure and cardiovascular death among patients with chronic heart failure …
[HTML][HTML] PD-1 blockade in mismatch repair–deficient, locally advanced rectal cancer
Background Neoadjuvant chemotherapy and radiation followed by surgical resection of the
rectum is a standard treatment for locally advanced rectal cancer. A subset of rectal cancer is …
rectum is a standard treatment for locally advanced rectal cancer. A subset of rectal cancer is …
Masks and coronavirus disease 2019 (COVID-19)
AN Desai, DM Aronoff - Jama, 2020 - jamanetwork.com
Why Should I Consider Wearing a Face Mask? Recent studies suggest that coronavirus
disease 2019 (COVID-19) …
disease 2019 (COVID-19) …
[HTML][HTML] Dapagliflozin in patients with heart failure and reduced ejection fraction
…, VK Chopra, RA de Boer, AS Desai… - … England Journal of …, 2019 - Mass Medical Soc
Background In patients with type 2 diabetes, inhibitors of sodium–glucose cotransporter 2 (SGLT2)
reduce the risk of a first hospitalization for heart failure, possibly through glucose-…
reduce the risk of a first hospitalization for heart failure, possibly through glucose-…
[HTML][HTML] Sorafenib in advanced clear-cell renal-cell carcinoma
…, C Chevreau, E Solska, AA Desai… - … England Journal of …, 2007 - Mass Medical Soc
Background We conducted a phase 3, randomized, double-blind, placebo-controlled trial of
sorafenib, a multikinase inhibitor of tumor-cell proliferation and angiogenesis, in patients …
sorafenib, a multikinase inhibitor of tumor-cell proliferation and angiogenesis, in patients …
[HTML][HTML] Angiotensin–neprilysin inhibition versus enalapril in heart failure
Background We compared the angiotensin receptor–neprilysin inhibitor LCZ696 with
enalapril in patients who had heart failure with a reduced ejection fraction. In previous studies, …
enalapril in patients who had heart failure with a reduced ejection fraction. In previous studies, …