User profiles for A. Csikasz-Nagy
Attila Csikász-NagyPázmány Péter Catholic University, Hungary Verified email at itk.ppke.hu Cited by 4943 |
The dynamics of cell cycle regulation
Major events of the cell cycle—DNA synthesis, mitosis and cell division—are regulated by a
complex network of protein interactions that control the activities of cyclin‐dependent kinases…
complex network of protein interactions that control the activities of cyclin‐dependent kinases…
Integrative analysis of cell cycle control in budding yeast
KC Chen, L Calzone, A Csikasz-Nagy… - Molecular biology of …, 2004 - Am Soc Cell Biol
The adaptive responses of a living cell to internal and external signals are controlled by
networks of proteins whose interactions are so complex that the functional integration of the …
networks of proteins whose interactions are so complex that the functional integration of the …
Computational systems biology of the cell cycle
A Csikasz-Nagy - Briefings in bioinformatics, 2009 - academic.oup.com
One of the early success stories of computational systems biology was the work done on cell-cycle
regulation. The earliest mathematical descriptions of cell-cycle control evolved into …
regulation. The earliest mathematical descriptions of cell-cycle control evolved into …
[HTML][HTML] The cell cycle switch computes approximate majority
L Cardelli, A Csikász-Nagy - Scientific reports, 2012 - nature.com
Both computational and biological systems have to make decisions about switching from
one state to another. The ‘Approximate Majority’ computational algorithm provides the …
one state to another. The ‘Approximate Majority’ computational algorithm provides the …
[HTML][HTML] Analysis of a generic model of eukaryotic cell-cycle regulation
We propose a protein interaction network for the regulation of DNA synthesis and mitosis
that emphasizes the universality of the regulatory system among eukaryotic cells. The …
that emphasizes the universality of the regulatory system among eukaryotic cells. The …
Kinetic analysis of a molecular model of the budding yeast cell cycle
KC Chen, A Csikasz-Nagy, B Gyorffy, J Val… - Molecular biology of …, 2000 - Am Soc Cell Biol
The molecular machinery of cell cycle control is known in more detail for budding yeast,
Saccharomyces cerevisiae, than for any other eukaryotic organism. In recent years, many …
Saccharomyces cerevisiae, than for any other eukaryotic organism. In recent years, many …
[HTML][HTML] The critical size is set at a single-cell level by growth rate to attain homeostasis and adaptation
…, E Garí, C Gallego, A Csikász-Nagy… - Nature …, 2012 - nature.com
Budding yeast cells are assumed to trigger Start and enter the cell cycle only after they attain
a critical size set by external conditions. However, arguing against deterministic models of …
a critical size set by external conditions. However, arguing against deterministic models of …
Irreversible cell-cycle transitions are due to systems-level feedback
The irreversibility of cell-cycle transitions is commonly thought to derive from the irreversible
degradation of certain regulatory proteins. We argue that irreversible transitions in the cell …
degradation of certain regulatory proteins. We argue that irreversible transitions in the cell …
Circadian rhythms synchronize mitosis in Neurospora crassa
…, WJ Belden, A Csikász-Nagy - Proceedings of the …, 2014 - National Acad Sciences
The cell cycle and the circadian clock communicate with each other, resulting in circadian-gated
cell division cycles. Alterations in this network may lead to diseases such as cancer. …
cell division cycles. Alterations in this network may lead to diseases such as cancer. …
[HTML][HTML] An insulin-to-insulin regulatory network orchestrates phenotypic specificity in development and physiology
Insulin-like peptides (ILPs) play highly conserved roles in development and physiology.
Most animal genomes encode multiple ILPs. Here we identify mechanisms for how the forty …
Most animal genomes encode multiple ILPs. Here we identify mechanisms for how the forty …