User profiles for A. Crist

Alex Krist

- Verified email at vcu.edu - Cited by 28035

Angelika N Christ

- Verified email at uq.edu.au - Cited by 13758

[PDF][PDF] Western diet and the immune system: an inflammatory connection

A Christ, M Lauterbach, E Latz - Immunity, 2019 - cell.com
The consumption of Western-type calorically rich diets combined with chronic overnutrition
and a sedentary lifestyle in Western societies evokes a state of chronic metabolic …

Genomic analyses identify molecular subtypes of pancreatic cancer

…, AL Johns, AM Patch, MC Gingras, DK Miller, AN Christ… - Nature, 2016 - nature.com
Integrated genomic analysis of 456 pancreatic ductal adenocarcinomas identified 32 recurrently
mutated genes that aggregate into 10 pathways: KRAS, TGF-β, WNT, NOTCH, ROBO/…

Whole genomes redefine the mutational landscape of pancreatic cancer

…, AJ Robertson, MZH Fadlullah, TJC Bruxner, AN Christ… - Nature, 2015 - nature.com
Pancreatic cancer remains one of the most lethal of malignancies and a major health burden.
We performed whole-genome sequencing and copy number variation (CNV) analysis of …

Whole–genome characterization of chemoresistant ovarian cancer

…, S Manning, S Idrisoglu, TJC Bruxner, AN Christ… - Nature, 2015 - nature.com
Patients with high-grade serous ovarian cancer (HGSC) have experienced little
improvement in overall survival, and standard treatment has not advanced beyond platinum-based …

Whole-genome landscape of pancreatic neuroendocrine tumours

…, S McKay, MCJ Quinn, TJC Bruxner, AN Christ… - Nature, 2017 - nature.com
The diagnosis of pancreatic neuroendocrine tumours (PanNETs) is increasing owing to
more sensitive detection methods, and this increase is creating challenges for clinical …

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

…, S Wood, Q Xu, K Nones, J Lynn Fink, A Christ… - Nature, 2012 - nature.com
Pancreatic cancer is a highly lethal malignancy with few effective therapies. We performed
exome sequencing and copy number analysis to define genomic aberrations in a …

Screening for colorectal cancer: US Preventive Services Task Force recommendation statement

…, EM Davis, KE Donahue, CA Doubeni, AH Krist… - Jama, 2021 - jamanetwork.com
Importance Colorectal cancer is the third leading cause of cancer death for both men and
women, with an estimated 52 980 persons in the US projected to die of colorectal cancer in …

Screening for lung cancer: US Preventive Services Task Force recommendation statement

AH Krist, KW Davidson, CM Mangione, MJ Barry… - Jama, 2021 - jamanetwork.com
Importance Lung cancer is the second most common cancer and the leading cause of cancer
death in the US. In 2020, an estimated 228 820 persons were diagnosed with lung cancer, …

Screening for colorectal cancer: US Preventive Services Task Force recommendation statement

…, MW Gillman, DM Harper, AR Kemper, AH Krist… - Jama, 2016 - jamanetwork.com
Importance Colorectal cancer is the second leading cause of cancer death in the United States.
In 2016, an estimated 134 000 persons will be diagnosed with the disease, and about 49 …

The Virtual Family—development of surface-based anatomical models of two adults and two children for dosimetric simulations

A Christ, W Kainz, EG Hahn, K Honegger… - Physics in Medicine …, 2009 - iopscience.iop.org
The objective of this study was to develop anatomically correct whole body human models
of an adult male (34 years old), an adult female (26 years old) and two children (an 11-year-…