[HTML][HTML] Plant genome editing made easy: targeted mutagenesis in model and crop plants using the CRISPR/Cas system

K Belhaj, A Chaparro-Garcia, S Kamoun, V Nekrasov - Plant methods, 2013 - Springer
Targeted genome engineering (also known as genome editing) has emerged as an alternative
to classical plant breeding and transgenic (GMO) methods to improve crop plants. Until …

Editing plant genomes with CRISPR/Cas9

K Belhaj, A Chaparro-Garcia, S Kamoun… - Current opinion in …, 2015 - Elsevier
Highlights • Cas9 is an RNA-guided DNA endonuclease innate to prokaryotic immune
systems. • CRISPR/Cas9 has recently emerged as a powerful genome editing tool. • CRISPR/…

Effector biology of plant-associated organisms: concepts and perspectives

J Win, A Chaparro-Garcia, K Belhaj… - Cold Spring Harbor …, 2012 - symposium.cshlp.org
Every plant is closely associated with a variety of living organisms. Therefore, deciphering
how plants interact with mutualistic and parasitic organisms is essential for a comprehensive …

Adaptive evolution has targeted the C-terminal domain of the RXLR effectors of plant pathogenic oomycetes

…, KV Krasileva, LM Cano, A Chaparro-Garcia… - The Plant …, 2007 - academic.oup.com
Oomycete plant pathogens deliver effector proteins inside host cells to modulate plant defense
circuitry and to enable parasitic colonization. These effectors are defined by a conserved …

Elicitin recognition confers enhanced resistance to Phytophthora infestans in potato

J Du, E Verzaux, A Chaparro-Garcia, G Bijsterbosch… - Nature plants, 2015 - nature.com
Potato late blight, caused by the destructive Irish famine pathogen Phytophthora infestans,
is a major threat to global food security 1, 2. All late blight resistance genes identified to date …

[HTML][HTML] The receptor-like kinase SERK3/BAK1 is required for basal resistance against the late blight pathogen Phytophthora infestans in Nicotiana benthamiana

A Chaparro-Garcia, RC Wilkinson, S Gimenez-Ibanez… - PloS one, 2011 - journals.plos.org
Background The filamentous oomycete plant pathogen Phytophthora infestans causes late
blight, an economically important disease, on members of the nightshade family (Solanaceae…

Ten things to know about oomycete effectors

…, S Raffaele, A CHAPARROGARCIA… - Molecular plant …, 2009 - Wiley Online Library
Long considered intractable organisms by fungal genetic research standards, the oomycetes
have recently moved to the centre stage of research on plant–microbe interactions. Recent …

Phosphatidylinositol monophosphate-binding interface in the oomycete RXLR effector AVR3a is required for its stability in host cells to modulate plant immunity

T Yaeno, H Li, A Chaparro-Garcia… - Proceedings of the …, 2011 - National Acad Sciences
The oomycete pathogen Phytophthora infestans causes potato late blight, one of the most
economically damaging plant diseases worldwide. P. infestans produces AVR3a, an essential …

Emerging oomycete threats to plants and animals

…, A Chaparro-Garcia… - … of the Royal …, 2016 - royalsocietypublishing.org
Oomycetes, or water moulds, are fungal-like organisms phylogenetically related to algae.
They cause devastating diseases in both plants and animals. Here, we describe seven …

Single Amino Acid Mutations in the Potato Immune Receptor R3a Expand Response to Phytophthora Effectors

…, M Franceschetti, A Chaparro-Garcia… - Molecular Plant …, 2014 - Am Phytopath Society
Both plants and animals rely on nucleotide-binding domain and leucine-rich repeat-containing
(NB-LRR or NLR) proteins to respond to invading pathogens and activate immune …