User profiles for A. Caudy
 | Amy CaudyPrincipal, Maple Flavored Solutions Verified email at mapleflavoredsolutions.com Cited by 24324 |
Post-transcriptional gene silencing by double-stranded RNA
Imagine being able to knock out your favourite gene with only a day's work. Not just in one
model system, but in virtually any organism: plants, flies, mice or cultured cells. This sort of …
model system, but in virtually any organism: plants, flies, mice or cultured cells. This sort of …
Uniform nomenclature for the mitochondrial contact site and cristae organizing system
…, P Amati, RA Capaldi, AA Caudy… - Journal of Cell …, 2014 - rupress.org
The mitochondrial inner membrane contains a large protein complex that functions in inner
membrane organization and formation of membrane contact sites. The complex was variably …
membrane organization and formation of membrane contact sites. The complex was variably …
Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells
PJ Paddison, AA Caudy, E Bernstein… - Genes & …, 2002 - genesdev.cshlp.org
RNA interference (RNAi) was first recognized inCaenorhabditis elegans as a biological
response to exogenous double-stranded RNA (dsRNA), which induces sequence-specific gene …
response to exogenous double-stranded RNA (dsRNA), which induces sequence-specific gene …
Fragile X-related protein and VIG associate with the RNA interference machinery
RNA interference (RNAi) is a flexible gene silencing mechanism that responds to double-stranded
RNA by suppressing homologous genes. Here, we report the characterization of …
RNA by suppressing homologous genes. Here, we report the characterization of …
Stable suppression of gene expression by RNAi in mammalian cells
PJ Paddison, AA Caudy… - Proceedings of the …, 2002 - National Acad Sciences
In a diverse group of organisms including plants, Caenorhabditis elegans, Drosophila, and
trypanosomes, double-stranded RNA (dsRNA) is a potent trigger of gene silencing. In several …
trypanosomes, double-stranded RNA (dsRNA) is a potent trigger of gene silencing. In several …
CD25 deficiency causes an immune dysregulation, polyendocrinopathy, enteropathy, X-linked–like syndrome, and defective IL-10 expression from CD4 lymphocytes
BACKGROUND: Immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX)
results in systemic autoimmunity from birth and can be caused by mutations in the …
results in systemic autoimmunity from birth and can be caused by mutations in the …
Dissection of genetically complex traits with extremely large pools of yeast segregants
Most heritable traits, including many human diseases 1 , are caused by multiple loci. Studies
in both humans and model organisms, such as yeast, have failed to detect a large fraction …
in both humans and model organisms, such as yeast, have failed to detect a large fraction …
Role for a bidentate ribonuclease in the initiation step of RNA interference
RNA interference (RNAi) is the mechanism through which double-stranded RNAs silence
cognate genes 1 , 2 , 3 , 4 , 5 . In plants, this can occur at both the transcriptional and the post-…
cognate genes 1 , 2 , 3 , 4 , 5 . In plants, this can occur at both the transcriptional and the post-…
Regulation of transcriptional activation domain function by ubiquitin
SE Salghetti, AA Caudy, JG Chenoweth, WP Tansey - Science, 2001 - science.org
The ability of transcriptional activation domains (TADs) to signal ubiquitin-mediated proteolysis
suggests an involvement of the ubiquitin-proteasome pathway in transcription. To probe …
suggests an involvement of the ubiquitin-proteasome pathway in transcription. To probe …
Argonaute2, a link between genetic and biochemical analyses of RNAi
SM Hammond, S Boettcher, AA Caudy, R Kobayashi… - Science, 2001 - science.org
Double-stranded RNA induces potent and specific gene silencing through a process
referred to as RNA interference (RNAi) or posttranscriptional gene silencing (PTGS). RNAi is …
referred to as RNA interference (RNAi) or posttranscriptional gene silencing (PTGS). RNAi is …