Purpose: To analytically and clinically validate microsatellite instability (MSI) detection using
cell-free DNA (cfDNA) sequencing. Experimental Design: Pan-cancer MSI detection using …

Rapidly evolving RNA viruses continuously produce minority haplotypes that can become
dominant if they are drug-resistant or can better evade the immune system. Therefore, early …

Migraine is one of the most common types of headache, which can lead to a significant
decrease in quality of life. Researchers identify migraine with aura, migraine without aura, and …

Objectives To assess the reliability and validity of age-specific versions of the Fibrodysplasia
Ossificans Progressiva Physical Function Questionnaire (FOP-PFQ), developed to measure …

Background RNA viruses such as HCV and HIV mutate at extremely high rates, and as a
result, they exist in infected hosts as populations of genetically related variants. Recent …

As a result of a high rate of mutations and recombination events, an RNA-virus exists as a
heterogeneous “swarm” of mutant variants. The long read length offered by single-molecule …

Highly mutable RNA viruses such as influenza A virus, human immunodeficiency virus and
hepatitis C virus exist in infected hosts as highly heterogeneous populations of closely …

The Russian experts’ guidelines on evaluation and treatment of medication-overuse
headache are based on evidence-based medicine, the latest revision of the International …

Background Highly mutable RNA viruses exist in infected hosts as heterogeneous populations
of genetically close variants known as quasispecies. Next-generation sequencing (NGS) …

2-Nitro-1H-benzo[f]chromenes reacted with alcohols to give a series of 3-alkoxy-2-nitro-2,3-dihydro-1H-benzo[f]chromenes
as mixtures of cis and trans isomers. The reaction of 2-nitro-…