Intracellular processes rarely work in isolation but continually interact with the rest of the cell.
In microbes, for example, we now know that gene expression across the whole genome …

Embryonic stem cell (ESC) pluripotency is governed by a gene regulatory network centered
on the transcription factors Oct4 and Nanog. To date, robust self-renewing ESC states have …

Growth impacts a range of phenotypic responses. Identifying the sources of growth variation
and their propagation across the cellular machinery can thus unravel mechanisms that …

Synthetic gene circuits perturb the physiology of their cellular host. The extra load on
endogenous processes shifts the equilibrium of resource allocation in the host, leading to slow …

Accurate in silico prediction of protein–ligand binding affinity is important in the early stages
of drug discovery. Deep learning-based methods exist but have yet to overtake more …

Background To characterise the longitudinal dynamics of C-reactive protein (CRP) and
Procalcitonin (PCT) in a cohort of hospitalised patients with COVID-19 and support antimicrobial …

Background Understanding nosocomial acquisition, outbreaks, and transmission chains in
real time will be fundamental to ensuring infection-prevention measures are effective in …

The t complex responder (Tcr) encoded by the mouse t haplotype is able to cause
phenotypic differences between t and + sperm derived from t/+ males, leading to non-Mendelian …

Background Real-time prediction is key to prevention and control of infections associated
with health-care settings. Contacts enable spread of many infections, yet most risk prediction …

… Andrea Y Weiße , Andrea Y Weiße … Jonathan A Otter, Siddharth Mookerjee, Frances Davies,
Frances Bolt, Eleonora Dyakova, Yeeshika Shersing, Adhiratha Boonyasiri, Andrea Y Weiße…