User profiles for A. X. Carvalho

Alexandre Xavier Ywata de Carvalho

Secretaria Especial de Competitividade e Produtividade
Verified email at ipea.gov.br
Cited by 2200

Molecular mechanism of dynein recruitment to kinetochores by the Rod–Zw10–Zwilch complex and Spindly

…, HR Pires, C Carvalho, J Amorim, AX Carvalho… - Journal of Cell …, 2017 - rupress.org
… Pereira, PA Simões, and AX Carvalho conceived and designed … Carvalho. RM Reis
performed the tissue culture work. DJ … with advice from DK Cheerambathur and AX Carvalho. …

JIP3 interacts with dynein and kinesin-1 to regulate bidirectional organelle transport

…, EA d'Amico, A Musacchio, AX Carvalho… - Journal of Cell …, 2022 - rupress.org
The MAP kinase and motor scaffold JIP3 prevents excess lysosome accumulation in axons of
vertebrates and invertebrates. How JIP3’s interaction with dynein and kinesin-1 contributes …

[HTML][HTML] Network contractility during cytokinesis—from molecular to global views

J Leite, DS Osorio, AF Sobral, AM Silva, AX Carvalho - Biomolecules, 2019 - mdpi.com
Cytokinesis is the last stage of cell division, which partitions the mother cell into two
daughter cells. It requires the assembly and constriction of a contractile ring that consists of a …

[PDF][PDF] Self-assembly of the RZZ complex into filaments drives kinetochore expansion in the absence of microtubule attachment

…, R Celestino, DK Cheerambathur, AX Carvalho… - Current Biology, 2018 - cell.com
The kinetochore is a dynamic multi-protein assembly that forms on each sister chromatid
and interacts with microtubules of the mitotic spindle to drive chromosome segregation. In …

[HTML][HTML] High-resolution temporal analysis reveals a functional timeline for the molecular regulation of cytokinesis

…, V Chand, JA Sees, K Laband, AX Carvalho… - Developmental cell, 2014 - cell.com
To take full advantage of fast-acting temperature-sensitive mutations, thermal control must
be extremely rapid. We developed the Therminator, a device capable of shifting sample …

TPXL-1 activates Aurora A to clear contractile ring components from the polar cortex during cytokinesis

…, T Kim, DS Osório, F Motegi, AX Carvalho… - Journal of Cell …, 2018 - rupress.org
During cytokinesis, a signal from the central spindle that forms between the separating
anaphase chromosomes promotes the accumulation of contractile ring components at the cell …

The ARP2/3 complex prevents excessive formin activity during cytokinesis

…, K Oegema, R Gassmann, AX Carvalho - Molecular biology of …, 2019 - Am Soc Cell Biol
Cytokinesis completes cell division by constriction of an actomyosin contractile ring that
separates the two daughter cells. Here we use the early Caenorhabditis elegans embryo to …

[HTML][HTML] A transient helix in the disordered region of dynein light intermediate chain links the motor to structurally diverse adaptors for cargo transport

…, DJ Barbosa, A Born, PJ Nichols, AX Carvalho… - PLoS …, 2019 - journals.plos.org
All animal cells use the motor cytoplasmic dynein 1 (dynein) to transport diverse cargo
toward microtubule minus ends and to organize and position microtubule arrays such as the …

WDR60-mediated dynein-2 loading into cilia powers retrograde IFT and transition zone crossing

…, MJG De-Castro, N Vieira, C Vieira, AX Carvalho… - Journal of Cell …, 2021 - rupress.org
… Gassmann and AX Carvalho provided strains, reagents, and equipment and helped with
experimental design. TJ Dantas and CMC Abreu conceived the project, designed and helped …

Learning and pricing in an internet environment with binomial demands

AX Carvalho, ML Puterman - Journal of Revenue and Pricing …, 2005 - Springer
… This paper extends the work of Carvalho and Puterman (2003) by replacing a lognormal
demand distribution with a binomial demand distribution (see the next section for differences in …