User profiles for A. T. Kalinka
Alex T KalinkaCancer Research UK (TDL), Cambridge Verified email at cancer.org.uk Cited by 1970 |
The evolution of early animal embryos: conservation or divergence?
AT Kalinka, P Tomancak - Trends in ecology & evolution, 2012 - cell.com
… In 1922, Walter Garstang placed the embryo back at the heart of evolution by arguing that
the origins of adult morphological novelties must often be traced back to changes in the …
the origins of adult morphological novelties must often be traced back to changes in the …
Introns and gene expression: cellular constraints, transcriptional regulation, and evolutionary consequences
… to be evolutionarily young hints at links between cellular … The range of these values may
be, at least in part, due to the … pressure to keep the exon length at ∼140 bp 10, approximately …
be, at least in part, due to the … pressure to keep the exon length at ∼140 bp 10, approximately …
Gene expression divergence recapitulates the developmental hourglass model
… We quantify divergence at different times during embryogenesis, and show that expression
… By fitting different evolutionary models to each gene, we show that at each time point more …
… By fitting different evolutionary models to each gene, we show that at each time point more …
Abundant Occurrence of Basal Radial Glia in the Subventricular Zone of Embryonic Neocortex of a Lissencephalic Primate, the Common Marmoset Callithrix jacchus
I Kelava, I Reillo, AY Murayama, AT Kalinka… - Cerebral …, 2012 - academic.oup.com
… bRG cells, expressing Pax6, Sox2 (but not Tbr2), glutamate aspartate transporter, and
glial fibrillary acidic protein and retaining a basal process at mitosis, occur at similar relative …
glial fibrillary acidic protein and retaining a basal process at mitosis, occur at similar relative …
[PDF][PDF] The earliest transcribed zygotic genes are short, newly evolved, and different across species
… significant transcriptional activity exists at fertilization. We show that … at other developmental
stages. Comparison of fish, fly, and mouse data revealed different sets of genes expressed at …
stages. Comparison of fish, fly, and mouse data revealed different sets of genes expressed at …
linkcomm: an R package for the generation, visualization, and analysis of link communities in networks of arbitrary size and type
AT Kalinka, P Tomancak - Bioinformatics, 2011 - academic.oup.com
… After assigning pairwise similarities to all of the links in the network, the links are hierarchically
clustered and the resulting dendrogram is cut at a point that maximizes the density of links …
clustered and the resulting dendrogram is cut at a point that maximizes the density of links …
[HTML][HTML] An adaptive threshold in mammalian neocortical evolution
… We arrived at two models that show the highest reliability for predicting cortical neuron
numbers in a range of species: a mouse neurogenic program, which implicates only …
numbers in a range of species: a mouse neurogenic program, which implicates only …
Systematic imaging reveals features and changing localization of mRNAs in Drosophila development
H Jambor, V Surendranath, AT Kalinka, P Mejstrik… - Elife, 2015 - elifesciences.org
… the different time-points of oogenesis the number of localized mRNAs varied; it was the
highest at stage 2–7 and dropped to around 100 mRNAs at stage 8 and increased only slightly …
highest at stage 2–7 and dropped to around 100 mRNAs at stage 8 and increased only slightly …
Androgens increase excitatory neurogenic potential in human brain organoids
… experiment was started at 17 days, and hormones were removed from the medium at 35
days. Organoids were then grown in IDM+A with dissolved Matrigel and fixed at 52 and 75 days. …
days. Organoids were then grown in IDM+A with dissolved Matrigel and fixed at 52 and 75 days. …
How did viviparity originate and evolve? Of conflict, co‐option, and cryptic choice
AT Kalinka - BioEssays, 2015 - Wiley Online Library
… yolk, fertilized internally, and laid at a relatively early stage of … reproductive tract and
oviposited at an advanced stage of … The full text of this article hosted at iucr.org is unavailable …
oviposited at an advanced stage of … The full text of this article hosted at iucr.org is unavailable …