User profiles for A. S. Konagurthu

Arun Konagurthu

Department of Data Science and AI, Monash University
Verified email at monash.edu
Cited by 1281

MUSTANG: a multiple structural alignment algorithm

AS Konagurthu, JC Whisstock… - Proteins: Structure …, 2006 - Wiley Online Library
Multiple structural alignment is a fundamental problem in structural genomics. In this article,
we define a reliable and robust algorithm, MUSTANG (MUltiple STructural AligNment …

Sequence and structure alignments in post-AlphaFold era

S Rajapaksa, AS Konagurthu, AM Lesk - Current Opinion in Structural …, 2023 - Elsevier
Sequence alignment is fundamental for analyzing protein structure and function. For all but
closely-related proteins, alignments based on structures are more accurate than alignments …

Minimum message length inference of secondary structure from protein coordinate data

AS Konagurthu, AM Lesk, L Allison - Bioinformatics, 2012 - academic.oup.com
Motivation: Secondary structure underpins the folding pattern and architecture of most
proteins. Accurate assignment of the secondary structure elements is therefore an important …

Osmotic capsules: a universal oral, controlled-release drug delivery dosage form

KC Waterman, GS Goeken, S Konagurthu… - Journal of controlled …, 2011 - Elsevier
An osmotic, oral, controlled-release capsule is described. This capsule provides drug delivery
at fixed delivery rates (T 80% = 6 or 14 h) independent of drug properties (eg, solubility) or …

[HTML][HTML] On the origin of distribution patterns of motifs in biological networks

AS Konagurthu, AM Lesk - BMC Systems Biology, 2008 - Springer
Background Inventories of small subgraphs in biological networks have identified commonly-recurring
patterns, called motifs. The inference that these motifs have been selected for …

[HTML][HTML] MUSTANG-MR structural sieving server: applications in protein structural analysis and crystallography

AS Konagurthu, CF Reboul, JW Schmidberger… - PLoS …, 2010 - journals.plos.org
Background A central tenet of structural biology is that related proteins of common function
share structural similarity. This has key practical consequences for the derivation and …

On the reliability and the limits of inference of amino acid sequence alignments

…, D Abramson, AS Konagurthu - …, 2022 - academic.oup.com
Motivation Alignments are correspondences between sequences. How reliable are alignments
of amino acid sequences of proteins, and what inferences about protein relationships can …

Statistical inference of protein structural alignments using information and compression

…, M Garcia de la Banda, AS Konagurthu - …, 2017 - academic.oup.com
Motivation Structural molecular biology depends crucially on computational techniques that
compare protein three-dimensional structures and generate structural alignments (the …

Use of ultrasonic time‐domain reflectometry for real‐time measurement of thickness changes during evaporative casting of polymeric films

WFC Kools, S Konagurthu… - Journal of applied …, 1998 - Wiley Online Library
The dry‐cast membrane‐formation process is a principal technique by which asymmetric
porous membranes as well as dense films can be obtained. Much insight into the fundamental …

Structural search and retrieval using a tableau representation of protein folding patterns

AS Konagurthu, PJ Stuckey, AM Lesk - Bioinformatics, 2008 - academic.oup.com
Abstract Comparison and classification of folding patterns from a database of protein
structures is crucial to understand the principles of protein architecture, evolution and function. …