We aimed to obtain reliable reference charts for sleep duration, estimate the prevalence of
sleep complaints across the lifespan and identify risk indicators of poor sleep. Studies were …

Obesity is globally prevalent and highly heritable, but its underlying genetic factors remain
largely elusive. To identify genetic loci for obesity susceptibility, we examined associations …

Obesity is heritable and predisposes to many diseases. To understand the genetic basis of
obesity better, here we conduct a genome-wide association study and Metabochip meta-…

Most common human traits and diseases have a polygenic pattern of inheritance: DNA
sequence variants at many genetic loci influence the phenotype. Genome-wide association (GWA…

Using genome-wide data from 253,288 individuals, we identified 697 variants at genome-wide
significance that together explained one-fifth of the heritability for adult height. By testing …

… As reported in Wood et al. (5), we found that including SNPs beyond GWS increases …
Summary statistics of GWAS of height and BMI from Wood et al. (5) and Locke et al. (6) studies were …

Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic
outcomes, independent of overall adiposity. To increase our understanding of the genetic …

Bone mineral density (BMD) is the most widely used predictor of fracture risk. We performed
the largest meta-analysis to date on lumbar spine and femoral neck BMD, including 17 …

Background Obesity is associated with vitamin D deficiency, and both are areas of active
public health concern. We explored the causality and direction of the relationship between …

Waist-hip ratio (WHR) is a measure of body fat distribution and a predictor of metabolic
consequences independent of overall adiposity. WHR is heritable, but few genetic variants …