… -osmotic shock, the resulting genomic expression program largely approximates the sum
of the gene expression responses to each individual transition (Gasch et al. 2000). This sug…

Unicellular fungi thrive in diverse niches around the world, and many of these niches
present unique and stressful challenges that must be contended with by their inhabitants. …

We explored genomic expression patterns in the yeastSaccharomyces cerevisiae responding
to diverse environmental transitions. DNA microarrays were used to measure changes in …

Healthy cells utilize intricate systems to monitor their environment and mount robust responses
in the event of cellular stress. Whether stress arises from external insults or defects due to …

Eukaryotic cells respond to DNA damage by arresting the cell cycle and modulating gene
expression to ensure efficient DNA repair. The human ATR kinase and its homolog in yeast, …

Background Organisms simplify the orchestration of gene expression by coregulating genes
whose products function together in the cell. Many proteins serve different roles depending …

In Saccharomyces cerevisiae, the Ca 2+ /calmodulin-dependent protein phosphatase,
calcineurin, is activated by specific environmental conditions, including exposure to Ca 2+ and Na …

… providing the W303 msn2Δmsn4Δ strain, Jessica Will for experimental assistance, the
UW-Madison Gene Expression Center for equipment usage, and members of the Gasch lab for …

The Zap1p transcription factor senses cellular zinc status and increases expression of its
target genes in response to zinc deficiency. Previously known Zap1p-regulated genes encode …

… , M Culbertson, J Yin, and the Gasch and Coon laboratories for constructive comments. SET
was … Gasch AP (2002b) Yeast genomic expression studies using DNA microarrays. Methods …