… Moreira 1 , TM Peixoto 2 , AM Siqueira 1 4 , CC Lamas 1 2 3 4 … Williams, AM Oster, M.
Fischer, et al. … Russell, SL Hills, AM Oster, CC Porse, G. Danyluk, M. Cone, et al. …

In spite of significant progress towards malaria control and elimination achieved in South
America in the 2000s, this mosquito-transmitted tropical disease remains an important public …

Background New World leishmaniasis is an important endemic disease and public health
problem in developing countries. The increase in ecologic tourism has extended this problem …

Importance There is no specific antiviral therapy recommended for coronavirus disease 2019
(COVID-19). In vitro studies indicate that the antiviral effect of chloroquine diphosphate (CQ…

Background In 2015, Brazil was faced with the cocirculation of three arboviruses of major
public health importance. The emergence of Zika virus (ZIKV) presents new challenges to both …

A 24-year-old housekeeper presented to hospital in Rio de Janeiro in June, 2014, with
headache, fever, and a rash, 5 days after waking with a severe generalised headache, retro-…

Background: Vaccines are urgently needed to tackle the unprecedented morbidity and mortality
of COVID-19. Administration of inactivated viruses are the common and mature platform …

Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant,
Gamma, emerged in the city of Manaus in late 2020 during a large resurgence of coronavirus …

Background Malaria was eliminated from southern and southeastern Brazil over 50 years
ago. However, an increasing number of autochthonous episodes attributed to Plasmodium …

We describe a case series of 17 patients hospitalized in Manaus (western Brazilian Amazon)
with PCR-confirmed Plasmodium vivax infection who were treated with chloroquine and …