[HTML][HTML] Pangenome-wide and molecular evolution analyses of the Pseudomonas aeruginosa species

…, AM Rada-Bravo, S Cárdenas-Brito, M Corredor… - BMC genomics, 2016 - Springer
Background Drug treatments and vaccine designs against the opportunistic human pathogen
Pseudomonas aeruginosa have multiple issues, all associated with the diverse genetic …

Caracterización molecular de bacilos Gram negativos productores de betalactamasas tipo carbapenemasas provenientes de centros hospitalarios de tres municipios …

AM Rada Bravo - 2020 - bibliotecadigital.udea.edu.co
Infections caused by multidrug-resistant (MDR) Gram-negative bacteria are a leading cause
of morbidity and mortality. Prolonged hospital stays and high health care costs in intensive …

Pangenome-wide and molecular evolution analyses of the Pseudonomas aeruginosa species

…, AM Rada Bravo - … de secuencia en …, 2015 - repositorio.minciencias.gov.co
Background. Duck treatments and vaccine designs against the opportunistic human pathogen
Pseudomonas aeruginosa have multiple issues, all associated with the diverse genetic …

[PDF][PDF] Graph-Based Data Analysis

HC Bravo - 2008 - Citeseer
… Development Core Team, 2007) as a result of the work on tree-structured covariance
matrices (Corrada Bravo, 2008). An interface to R was also created for the CSDP semidefinite …

[HTML][HTML] Genomic analyses of pneumococci reveal a wide diversity of bacteriocins–including pneumocyclicin, a novel circular bacteriocin

C Bogaardt, AJ van Tonder, AB Brueggemann - BMC genomics, 2015 - Springer
… was present because of prior experimental evidence for a role in immunity [20]; iii) bacteriocin
CDSs with multiple putative start codons close together were adapted to start at M(D/N)T; iv…

Comparative genomics of a drug-resistant Pseudomonas aeruginosa panel and the challenges of antimicrobial resistance prediction from genomes

J Jeukens, I Kukavica-Ibrulj… - FEMS Microbiology …, 2017 - academic.oup.com
Antimicrobial resistance (AMR) is now recognized as a global threat to human health. The
accessibility of microbial whole-genome sequencing offers an invaluable opportunity for …

Evidence for selection in the abundant accessory gene content of a prokaryote pangenome

FJ Whelan, RJ Hall, JO McInerney - Molecular biology and …, 2021 - academic.oup.com
A pangenome is the complete set of genes (core and accessory) present in a phylogenetic
clade. We hypothesize that a pangenome’s accessory gene content is structured and …

Evolutionary Genomics of Niche-Specific Adaptation to the Cystic Fibrosis Lung in Pseudomonas aeruginosa

JR Dettman, R Kassen - Molecular biology and evolution, 2021 - academic.oup.com
The comparative genomics of the transition of the opportunistic pathogen Pseudomonas
aeruginosa from a free-living environmental strain to one that causes chronic infection in the …

[HTML][HTML] Identification of pneumococcal colonization determinants in the stringent response pathway facilitated by genomic diversity

…, CM Thompson, K Trzciński, WP Hanage, M Lipsitch - BMC genomics, 2015 - Springer
Background Understanding genetic determinants of a microbial phenotype generally involves
creating and comparing isogenic strains differing at the locus of interest, but the naturally …

Selection Is a Significant Driver of Gene Gain and Loss in the Pangenome of the Bacterial Genus Sulfurovum in Geographically Distinct Deep-Sea Hydrothermal …

A Moulana, RE Anderson, CS Fortunato, JA Huber - Msystems, 2020 - Am Soc Microbiol
Microbial genomes have highly variable gene content, and the evolutionary history of microbial
populations is shaped by gene gain and loss mediated by horizontal gene transfer and …