… We thank Krichevsky laboratory members for insightful discussions and Dr. Kai-Christian
Sonntag for his careful reading of the manuscript. The work in the laboratory is supported by …

Glioblastomas are heterogeneous and invariably lethal tumours. They are characterized by
genetic and epigenetic variations among tumour cells, which makes the development of …

The Extracellular RNA Communication Consortium (ERCC) was launched to accelerate
progress in the new field of extracellular RNA (exRNA) biology and to establish whether …

Glioblastoma tumour cells release microvesicles (exosomes) containing mRNA, miRNA and
angiogenic proteins. These microvesicles are taken up by normal host cells, such as brain …

… JA Chan and AM Krichevsky contributed equally to this work. … (AM Krichevsky), and
Mahoney Center for Neuro-Oncology Fellowship at the Dana-Farber Cancer Institute (JA Chan). …

Several hundred microRNAs (miRNAs) have recently been cloned from a wide range of
organisms across phylogeny. Despite the high degree of conservation of miRNAs, their …

Substantial data indicate that microRNA 21 (miR-21) is significantly elevated in glioblastoma
(GBM) and in many other tumors of various origins. This microRNA has been implicated in …

MicroRNAs are a family of regulatory molecules involved in many physiological processes,
including differentiation and activation of cells of the immune system. We found that brain-…

MicroRNAs (miRNAs) are recently discovered small non-coding transcripts with a broad
spectrum of functions described mostly in invertebrates. As post-transcriptional regulators of …

RNA granules are a macromolecular structure observed in neurons, where they serve as
motile units that translocate mRNAs. Isolated RNA granules are highly enriched in Staufen …