User profiles for A. M. Dudley

Aimée M. Dudley

Senior Investigator & Interim Chief Scientific Officer, Pacific Northwest Research Institute
Verified email at pnri.org
Cited by 2929

A global view of pleiotropy and phenotypically derived gene function in yeast

AM Dudley, DM Janse, A Tanay, R Shamir… - Molecular systems …, 2005 - embopress.org
… In addition, all strains, except mrpl3, contained the correct gene deletion as determined by
PCR (Dutta, Dudley, and Church, unpublished results), a result that highlights errors that can …

Surface plasmon resonance biosensor for rapid label-free detection of microribonucleic acid at subfemtomole level

H Sipova, S Zhang, AM Dudley, D Galas… - Analytical …, 2010 - ACS Publications
Microribonucleic acids (miRNAs) have been linked with various regulatory functions and
disorders, such as cancers and heart diseases. They, therefore, present an important target for …

Measuring absolute expression with microarrays with a calibrated reference sample and an extended signal intensity range

AM Dudley, J Aach, MA Steffen… - Proceedings of the …, 2002 - National Acad Sciences
Gene expression ratios derived from spotted-glass microarray experiments have become
invaluable to researchers by providing sensitive and comprehensive indicators of the …

[HTML][HTML] Learning a prior on regulatory potential from eQTL data

SI Lee, AM Dudley, D Drubin, PA Silver… - PLoS …, 2009 - journals.plos.org
… spot formation could be due to differences in the properties of GFP and tdimer2 because
our inability to detect Puf3 fused to tdimer2 or other versions of red fluorescent protein (Dudley

The Spt components of SAGA facilitate TBP binding to a promoter at a post-activator-binding step in vivo

AM Dudley, C Rougeulle, F Winston - Genes & Development, 1999 - genesdev.cshlp.org
The SAGA complex of Saccharomyces cerevisiae is required for the transcription of many
RNA polymerase II-dependent genes. Previous studies have demonstrated that SAGA …

Genomic Sequence Diversity and Population Structure of Saccharomyces cerevisiae Assessed by RAD-seq

…, P May, AA Huang, AM Dudley… - G3: Genes …, 2013 - academic.oup.com
… Aimée M Dudley , Aimée M Dudley … and AM Dudley, unpublished data; Boekhout and Robert
2003). Colonies exhibiting these color phenotypes were picked and saved for further study. …

[HTML][HTML] Evaluation of methods for detection of fluorescence labeled subcellular objects in microscope images

…, J Selinummi, M Birbaumer, AM Dudley… - BMC …, 2010 - Springer
Background Several algorithms have been proposed for detecting fluorescently labeled
subcellular objects in microscope images. Many of these algorithms have been designed for …

Rapid Phenotypic and Genotypic Diversification After Exposure to the Oral Host Niche in Candida albicans

…, W Srifa, E Jeffery, D Abbey, SG Filler, AM Dudley… - Genetics, 2018 - academic.oup.com
… Aimée M Dudley , Aimée M Dudley … , Eric Jeffery, Darren Abbey, Scott G Filler, Aimée M
Dudley, Judith Berman, Rapid Phenotypic and Genotypic Diversification After Exposure to the …

[PDF][PDF] Independent origins of yeast associated with coffee and cacao fermentation

…, M Hays, C Field, EW Jeffery, JC Fay, AM Dudley - Current Biology, 2016 - cell.com
Modern transportation networks have facilitated the migration and mingling of previously
isolated populations of plants, animals, and insects. Human activities can also influence the …

Identifying regulatory mechanisms using individual variation reveals key role for chromatin modification

SI Lee, D Pe'er, AM Dudley… - Proceedings of the …, 2006 - National Acad Sciences
Sequence polymorphisms affect gene expression by perturbing the complex network of
regulatory interactions. We propose a probabilistic method, called Geronemo, which directly …