An upstream protein-coding region in enteroviruses modulates virus infection in gut epithelial cells
V Lulla, AM Dinan, M Hosmillo, Y Chaudhry… - Nature …, 2019 - nature.com
Enteroviruses comprise a large group of mammalian pathogens that includes poliovirus.
Pathology in humans ranges from sub-clinical to acute flaccid paralysis, myocarditis and …
Pathology in humans ranges from sub-clinical to acute flaccid paralysis, myocarditis and …
Translation initiation of leaderless and polycistronic transcripts in mammalian mitochondria
The synthesis of mitochondrial OXPHOS complexes is central to cellular metabolism, yet many
molecular details of mitochondrial translation remain elusive. It has been commonly held …
molecular details of mitochondrial translation remain elusive. It has been commonly held …
[HTML][HTML] Functional characterization of the Mycobacterium abscessus genome coupled with condition specific transcriptomics reveals conserved molecular strategies …
AA Miranda-CasoLuengo, PM Staunton, AM Dinan… - BMC genomics, 2016 - Springer
Background Mycobacterium abscessus subsp. abscessus (MAB) is a highly drug resistant
mycobacterium and the most common respiratory pathogen among the rapidly growing non-…
mycobacterium and the most common respiratory pathogen among the rapidly growing non-…
[PDF][PDF] Hybrid gene origination creates human-virus chimeric proteins during infection
…, M Chang, Y Fstkchyan, S Clohisey, AM Dinan… - Cell, 2020 - cell.com
RNA viruses are a major human health threat. The life cycles of many highly pathogenic RNA
viruses like influenza A virus (IAV) and Lassa virus depends on host mRNA, because viral …
viruses like influenza A virus (IAV) and Lassa virus depends on host mRNA, because viral …
A case for a negative-strand coding sequence in a group of positive-sense RNA viruses
AM Dinan, NI Lukhovitskaya, I Olendraite… - Virus …, 2020 - academic.oup.com
Positive-sense single-stranded RNA viruses form the largest and most diverse group of
eukaryote-infecting viruses. Their genomes comprise one or more segments of coding-sense …
eukaryote-infecting viruses. Their genomes comprise one or more segments of coding-sense …
Ribosome profiling of porcine reproductive and respiratory syndrome virus reveals novel features of viral gene expression
The arterivirus porcine reproductive and respiratory syndrome virus (PRRSV) causes
significant economic losses to the swine industry worldwide. Here we apply ribosome profiling (…
significant economic losses to the swine industry worldwide. Here we apply ribosome profiling (…
C6orf203 is an RNA-binding protein involved in mitochondrial protein synthesis
S Gopalakrishna, SF Pearce, AM Dinan… - Nucleic acids …, 2019 - academic.oup.com
In all biological systems, RNAs are associated with RNA-binding proteins (RBPs), forming
complexes that control gene regulatory mechanisms, from RNA synthesis to decay. In …
complexes that control gene regulatory mechanisms, from RNA synthesis to decay. In …
Comparative analysis of gene expression in virulent and attenuated strains of infectious bronchitis virus at subcodon resolution
AM Dinan, S Keep, E Bickerton, P Britton… - Journal of …, 2019 - Am Soc Microbiol
Like all coronaviruses, avian infectious bronchitis virus (IBV) possesses a long, single-stranded,
positive-sense RNA genome (∼27 kb) and has a complex replication strategy that …
positive-sense RNA genome (∼27 kb) and has a complex replication strategy that …
Transcriptional and translational landscape of equine torovirus
The genus Torovirus (subfamily Torovirinae , family Coronaviridae , order Nidovirales )
encompasses a range of species that infect domestic ungulates, including cattle, sheep, goats, …
encompasses a range of species that infect domestic ungulates, including cattle, sheep, goats, …
Relaxed selection drives a noisy noncoding transcriptome in members of the Mycobacterium tuberculosis complex
Related species are often used to understand the molecular underpinning of virulence
through examination of a shared set of biological features attributable to a core genome of …
through examination of a shared set of biological features attributable to a core genome of …