User profiles for A. J. Lea
 | Amanda J. LeaVanderbilt University Verified email at vanderbilt.edu Cited by 1878 |
Developmental plasticity: bridging research in evolution and human health
Early life experiences can have profound and persistent effects on traits expressed throughout
the life course, with consequences for later life behavior, disease risk, and mortality rates. …
the life course, with consequences for later life behavior, disease risk, and mortality rates. …
[HTML][HTML] Applying an evolutionary mismatch framework to understand disease susceptibility
Noncommunicable diseases (NCDs) are on the rise worldwide. Obesity, cardiovascular
disease, and type 2 diabetes are among a long list of “lifestyle” diseases that were rare …
disease, and type 2 diabetes are among a long list of “lifestyle” diseases that were rare …
Maximizing ecological and evolutionary insight in bisulfite sequencing data sets
Genome-scale bisulfite sequencing approaches have opened the door to ecological and
evolutionary studies of DNA methylation in many organisms. These approaches can be …
evolutionary studies of DNA methylation in many organisms. These approaches can be …
High social status males experience accelerated epigenetic aging in wild baboons
Aging, for virtually all life, is inescapable. However, within populations, biological aging
rates vary. Understanding sources of variation in this process is central to understanding the …
rates vary. Understanding sources of variation in this process is central to understanding the …
Mustard gas poisoning, chronic bronchitis, and lung cancer: an investigation into the possibility that poisoning by mustard gas in the 1914-18 war might be a factor in …
RAM Case, AJ Lea - British journal of preventive & social medicine, 1955 - ncbi.nlm.nih.gov
METHODS AND MATERIALS The ideal method of investigation would be to take all or a
random sample of the men known to have been gassed and to follow up their histories until the …
random sample of the men known to have been gassed and to follow up their histories until the …
[HTML][HTML] A flexible, efficient binomial mixed model for identifying differential DNA methylation in bisulfite sequencing data
Identifying sources of variation in DNA methylation levels is important for understanding gene
regulation. Recently, bisulfite sequencing has become a popular tool for investigating DNA …
regulation. Recently, bisulfite sequencing has become a popular tool for investigating DNA …
Genome-wide quantification of the effects of DNA methylation on human gene regulation
10.7554/eLife.37513.001 Changes in DNA methylation are involved in development, disease,
and the response to environmental conditions. However, not all regulatory elements are …
and the response to environmental conditions. However, not all regulatory elements are …
Heritable victimization and the benefits of agonistic relationships
Here, we present estimates of heritability and selection on network traits in a single
population, allowing us to address the evolutionary potential of social behavior and the poorly …
population, allowing us to address the evolutionary potential of social behavior and the poorly …
Resource base influences genome‐wide DNA methylation levels in wild baboons (Papio cynocephalus)
Variation in resource availability commonly exerts strong effects on fitness‐related traits in
wild animals. However, we know little about the molecular mechanisms that mediate these …
wild animals. However, we know little about the molecular mechanisms that mediate these …
Dietary factors associated with death-rates from certain neoplasms in man.
AJ Lea - Lancet, 1966 - cabdirect.org
Data were from 24 countries and statistical comparisons were between death rates from
coronary disease and from neoplasms of breast, ovaries or rectum among women over 55 years …
coronary disease and from neoplasms of breast, ovaries or rectum among women over 55 years …