Inhibitor of growth protein-2 (ING2) is a nuclear adaptor protein that can regulate p53 and
histone acetylation in response to cellular stress and contains a PHD (plant homeodomain) …

Wnt signalling maintains the undifferentiated state of intestinal crypt/progenitor cells through
the TCF4/β‐catenin‐activating transcriptional complex. In colorectal cancer, activating …

Antibody profiling: native mass spectrometry analysis of intact antibodies can be achieved
with improved speed, sensitivity, and mass resolution by using a modified orbitrap instrument. …

The scarcity of primordial germ cells (PGCs) in the developing mammalian embryo hampers
robust biochemical analysis of the processes that underlie early germ cell formation. Here, …

The popularity of fat‐free fermented concentrated milk products, such as fresh cheeses and
high‐protein yogurt, has increased over the recent years, attributed to greater availability and …

SNARE proteins mediate fusion of intracellular eukaryotic membranes and their α-helical
transmembrane domains are known to contribute to lipid bilayer mixing. Synthetic …

Activation of the DNA‐damage checkpoint culminates in the inhibition of cyclin‐dependent
kinase (Cdk) complexes to prevent cell‐cycle progression. We have shown recently that Cdk …

Vanillyl‐alcohol oxidase (VAO; EC 1.1.3.38) contains a covalently 8α‐histidyl bound FAD,
which represents the most frequently encountered covalent flavin–protein linkage. To …

A central point of regulation in the Wnt/β-catenin signalling pathway is the formation of the β-catenin
destruction complex. Axin1, an essential negative regulator of Wnt signalling, serves …

The phosphoinositide phosphatidylinositol 4, 5-bisphosphate (PtdIns(4,5)P 2 ) is essential
for many cellular processes and is linked to the etiology of numerous human diseases [1–4]. …