User profiles for A. J. Enright

Anton Enright

Associate Professor, Department of Pathology, University of Cambridge
Verified email at cam.ac.uk
Cited by 52961

Prediction of microRNA targets

P Maziere, AJ Enright - Drug discovery today, 2007 - Elsevier
Recently, microRNAs (miRNAs) have been shown to be important regulators of genes in
many organisms and have already been implicated in a growing number of diseases. MiRNAs …

Computational prediction of protein–protein interactions

L Skrabanek, HK Saini, GD Bader, AJ Enright - Molecular biotechnology, 2008 - Springer
Recently a number of computational approaches have been developed for the prediction of
protein–protein interactions. Complete genome sequencing projects have provided the vast …

miRBase: tools for microRNA genomics

…, HK Saini, S Van Dongen, AJ Enright - Nucleic acids …, 2007 - academic.oup.com
miRBase is the central online repository for microRNA (miRNA) nomenclature, sequence
data, annotation and target prediction. The current release (10.0) contains 5071 miRNA loci …

miRBase: microRNA sequences, targets and gene nomenclature

…, S Van Dongen, A Bateman, AJ Enright - Nucleic acids …, 2006 - academic.oup.com
The miRBase database aims to provide integrated interfaces to comprehensive microRNA
sequence data, annotation and predicted gene targets. miRBase takes over functionality from …

[HTML][HTML] Human microRNA targets

B John, AJ Enright, A Aravin, T Tuschl, C Sander… - PLoS …, 2004 - journals.plos.org
MicroRNAs (miRNAs) interact with target mRNAs at specific sites to induce cleavage of the
message or inhibit translation. The specific function of most mammalian miRNAs is unknown. …

Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAs

…, RJ Grocock, S Van Dongen, K Inoue, AJ Enright… - science, 2006 - science.org
MicroRNAs (miRNAs) comprise 1 to 3% of all vertebrate genes, but their in vivo functions
and mechanisms of action remain largely unknown. Zebrafish miR-430 is expressed at the …

An efficient algorithm for large-scale detection of protein families

AJ Enright, S Van Dongen… - Nucleic acids research, 2002 - academic.oup.com
AJ Enright , AJ Enright … Finally, the RLCS algorithm (AJEnright, unpublished data) was
then used to determine a consensus annotation for each detected protein family. …

Classification schemes for protein structure and function

CA Ouzounis, RMR Coulson, AJ Enright… - Nature Reviews …, 2003 - nature.com
We examine the structural and functional classifications of the protein universe, providing
an overview of the existing classification schemes, their features and inter-relationships. We …

MicroRNAs regulate brain morphogenesis in zebrafish

AJ Giraldez, RM Cinalli, ME Glasner, AJ Enright… - Science, 2005 - science.org
MicroRNAs (miRNAs) are small RNAs that regulate gene expression posttranscriptionally.
To block all miRNA formation in zebrafish, we generated maternal-zygotic dicer (MZdicer) …

Requirement of bic/microRNA-155 for Normal Immune Function

…, PP Das, EA Miska, D Vetrie, K Okkenhaug, AJ Enright… - Science, 2007 - science.org
MicroRNAs are a class of small RNAs that are increasingly being recognized as important
regulators of gene expression. Although hundreds of microRNAs are present in the …