User profiles for A. J. Cox
 | Anthony J. CoxComputational Biology Group, Illumina Cambridge Ltd. Verified email at illumina.com Cited by 21326 |
Obesity, inflammation, and the gut microbiota
As the prevalence of obesity and associated disease continues to rise and concerns for the
spiralling economic and social costs also escalate, innovative management strategies …
spiralling economic and social costs also escalate, innovative management strategies …
Probiotics supplementation for athletes–clinical and physiological effects
Probiotic supplementation has traditionally focused on gut health. However, in recent years,
the clinical applications of probiotics have broadened to allergic, metabolic, inflammatory, …
the clinical applications of probiotics have broadened to allergic, metabolic, inflammatory, …
[HTML][HTML] Accurate whole human genome sequencing using reversible terminator chemistry
DNA sequence information underpins genetic research, enabling discoveries of important
biological or medical benefit. Sequencing projects have traditionally used long (400–800 …
biological or medical benefit. Sequencing projects have traditionally used long (400–800 …
[HTML][HTML] A comprehensive catalogue of somatic mutations from a human cancer genome
… Indels in the tumour and normal genomes were called using Pindel 39 , BWA 38 and
GROUPER (AJ Cox et al., manuscript in preparation) on the NCBI36 genome build. Pindel …
GROUPER (AJ Cox et al., manuscript in preparation) on the NCBI36 genome build. Pindel …
Manta: rapid detection of structural variants and indels for germline and cancer sequencing applications
We describe Manta, a method to discover structural variants and indels from next generation
sequencing data. Manta is optimized for rapid germline and somatic analysis, calling …
sequencing data. Manta is optimized for rapid germline and somatic analysis, calling …
SSAHA: a fast search method for large DNA databases
We describe an algorithm, SSAHA (SequenceSearch and Alignment by HashingAlgorithm),
for performing fast searches on databases containing multiple gigabases of DNA. …
for performing fast searches on databases containing multiple gigabases of DNA. …
[HTML][HTML] Modulation of allergic inflammation in the nasal mucosa of allergic rhinitis sufferers with topical pharmaceutical agents
Allergic rhinitis (AR) is a chronic upper respiratory disease estimated to affect between 10
and 40% of the worldwide population. The mechanisms underlying AR are highly complex …
and 40% of the worldwide population. The mechanisms underlying AR are highly complex …
The lux autoinducer regulates the production of exoenzyme virulence determinants in Erwinia carotovora and Pseudomonas aeruginosa.
…, M Birdsall, BW Bycroft, SR Chhabra, AJ Cox… - The EMBO …, 1993 - embopress.org
Erwinia carotovora and Pseudomonas aeruginosa secrete exoenzymes that contribute to
the pathogenesis of plant and mammalian infections respectively. E.carotovora mutants …
the pathogenesis of plant and mammalian infections respectively. E.carotovora mutants …
Increased renal expression of vascular endothelial growth factor (VEGF) and its receptor VEGFR-2 in experimental diabetes.
…, D Vranes, S Youssef, SA Stacker, AJ Cox… - Diabetes, 1999 - Am Diabetes Assoc
It has been suggested that the cytokine vascular endothelial growth factor (VEGF) has an
important role in the pathogenesis of diabetic retinopathy, but its role in nephropathy has not …
important role in the pathogenesis of diabetic retinopathy, but its role in nephropathy has not …
Experimental observation of magnetism in rhodium clusters
AJ Cox, JG Louderback, LA Bloomfield - Physical review letters, 1993 - APS
We have observed giant magnetic moments in clusters of rhodium, Rh n (n= 12–32), consistent
with ferromagnetic ordering of the 4d electrons. Ferromagnetic behavior has not been …
with ferromagnetic ordering of the 4d electrons. Ferromagnetic behavior has not been …