User profiles for A. G. Maule

Aaron Maule

Professor of Molecular Parasitology
Verified email at qub.ac.uk
Cited by 10731

[HTML][HTML] Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita

…, B Henrissat, JT Jones, V Laudet, AG Maule… - Nature …, 2008 - nature.com
Plant-parasitic nematodes are major agricultural pests worldwide and novel approaches to
control them are sorely needed. We report the draft genome sequence of the root-knot …

Stress alters immune function and disease resistance in chinook salmon (Oncorhynchus tshawytscha)

AG Maule, RA Tripp, SL Kaattari… - Journal of …, 1989 - joe.bioscientifica.com
We examined the effects of acute stress on the immune system and disease resistance of
juvenile chinook salmon ( Oncorhynchus tshawytscha ) in laboratory and clinical trials. Immune …

[HTML][HTML] Genomic Insights into the Origin of Parasitism in the Emerging Plant Pathogen Bursaphelenchus xylophilus

…, T Yokoi, MC Larsson, J Miwa, AG Maule… - PLoS …, 2011 - journals.plos.org
Bursaphelenchus xylophilus is the nematode responsible for a devastating epidemic of pine
wilt disease in Asia and Europe, and represents a recent, independent origin of plant …

Fasciola hepatica cathepsin L-like proteases: biology, function, and potential in the development of first generation liver fluke vaccines

…, A Mousley, N Kreshchenko, AG Maule… - International journal for …, 2003 - Elsevier
Fasciola hepatica secretes cathepsin L proteases that facilitate the penetration of the
parasite through the tissues of its host, and also participate in functions such as feeding and …

Changes in the Immune System of Coho Salmon (Oncorhynchus kisutch) during the Parr-to-Smolt Transformation and after Implantation of Cortisol

AG Maule, CB Schreck… - Canadian Journal of …, 1987 - cdnsciencepub.com
The primary immune response of coho salmon (Oncorhynchus kisutch), as assessed by the
production of splenic antibody-secreting cells (plaque-forming cells, PFC) after an injection …

The silencing of cysteine proteases in Fasciola hepatica newly excysted juveniles using RNA interference reduces gut penetration

…, JP Dalton, TW Spithill, TA Day, AG Maule - International journal for …, 2008 - Elsevier
Probing protein function in parasitic flatworms is hampered by the difficulties associated
with the development of transgenic approaches. Although RNA interference (RNAi) in …

[HTML][HTML] Cathepsin L1, the major protease involved in liver fluke (Fasciola hepatica) virulence: propeptide cleavage sites and autoactivation of the zymogen secreted …

…, GP Brennan, A Mousley, M Stewart, AG Maule… - Journal of Biological …, 2004 - ASBMB
The secretion and activation of the major cathepsin L1 cysteine protease involved in the
virulence of the helminth pathogen Fasciola hepatica was investigated. Only the fully processed …

Neuropeptide F: a novel parasitic flatworm regulatory peptide from Moniezia expansa (Cestoda: Cyclophyllidea)

AG Maule, C Shaw, DW Halton, L Thim, CF Johnston… - Parasitology, 1991 - cambridge.org
Using a C-terminally directed pancreatic polypeptide (PP) antiserum and immunocytochemical
methods, PP-immuno-reactivity (IR) was localized throughout the central (CNS) and …

flp gene disruption in a parasitic nematode reveals motor dysfunction and unusual neuronal sensitivity to RNA interference

…, TA Day, CC Fleming, AG Maule - The FASEB …, 2007 - Wiley Online Library
… Kimber, MJ, McKinney, S., McMaster, S., Day, TA, Fleming, CC, Maule, AG flp gene disruption
in a parasitic nematode reveals motor dysfunction and unusual neuronal sensitivity to RNA …

[HTML][HTML] RNAi effector diversity in nematodes

…, TA Day, A Mousley, NJ Marks, AG Maule - PLoS neglected …, 2011 - journals.plos.org
While RNA interference (RNAi) has been deployed to facilitate gene function studies in diverse
helminths, parasitic nematodes appear variably susceptible. To test if this is due to inter-…