The amount of radiologically dense breast-tissue appearing on a mammogram varies between
women because of differences in the composition of breast tissue, and is referred to here …

… Özdemir, Vural a,b ; Kalow, Werner a ; Tang, Bing-Kou a ; Paterson, Andrew D. b ; Walker, …
AD Paterson was the recipient of a postdoctoral fellowship from the Medical Research Council …

To study the effect of host genetics on gut microbiome composition, the MiBioGen consortium
curated and analyzed genome-wide genotypes and 16S fecal microbiome data from …

Although the role of genetics in personality has been studied extensively at a phenomenological
level, only lately has the investigation of specific genes been performed. Recent reports …

Rare copy-number variation (CNV) is an important source of risk for autism spectrum
disorders (ASDs). We analyzed 2,446 ASD-affected families and confirmed an excess of genic …

Individuals who are at risk for autosomal dominant polycystic kidney disease are often screened
by ultrasound using diagnostic criteria derived from individuals with mutations in PKD1. …

Refractive error is the most common eye disorder worldwide and is a prominent cause of
blindness. Myopia affects over 30% of Western populations and up to 80% of Asians. The …

While it is apparent that rare variation can play an important role in the genetic architecture
of autism spectrum disorders (ASDs), the contribution of common variation to the risk of …

Intestinal microbiota is known to be important in health and disease. Its composition is
influenced by both environmental and host factors. Few large-scale studies have evaluated the …

The goal of this pilot study was to explore the putative molecular mechanisms underlying
the phenotypic discordance of monozygotic (MZ) twins. Thus, patterns of epigenetic DNA …