User profiles for A. D. Beggs

Andrew Beggs

Professor of Surgery & Cancer Genetics
Verified email at bham.ac.uk
Cited by 26761

Peutz–Jeghers syndrome: a systematic review and recommendations for management

AD Beggs, AR Latchford, HFA Vasen, G Moslein… - Gut, 2010 - gut.bmj.com
Peutz–Jeghers syndrome (PJS, MIM175200) is an autosomal dominant condition defined
by the development of characteristic polyps throughout the gastrointestinal tract and …

[HTML][HTML] Nanopore sequencing and assembly of a human genome with ultra-long reads

…, AC Rand, TA Sasani, JR Tyson, AD Beggs… - Nature …, 2018 - nature.com
We report the sequencing and assembly of a reference genome for the human GM12878
Utah/Ceph cell line using the MinION (Oxford Nanopore Technologies) nanopore sequencer. …

A systematic review of transarterial embolization versus emergency surgery in treatment of major nonvariceal upper gastrointestinal bleeding

AD Beggs, MP Dilworth, SL Powell… - Clinical and …, 2014 - Taylor & Francis
Background Emergency surgery or transarterial embolization (TAE) are options for the
treatment of recurrent or refractory nonvariceal upper gastrointestinal bleeding. Surgery has the …

[HTML][HTML] Systematic review of donor and recipient predictive biomarkers of response to faecal microbiota transplantation in patients with ulcerative colitis

…, C Tselepis, RD Horniblow, N Sharma, AD Beggs… - …, 2022 - thelancet.com
Background Faecal microbiota transplantation (FMT) has previously been explored as a
treatment for ulcerative colitis (UC) however, biomarkers that predict and / or are associated with …

SARS-CoV-2 seroprevalence and asymptomatic viral carriage in healthcare workers: a cross-sectional study

…, AE Zielinska, M Crispin, DC Wraith, AD Beggs… - Thorax, 2020 - thorax.bmj.com
Objective To determine the rates of asymptomatic viral carriage and seroprevalence of
SARS-CoV-2 antibodies in healthcare workers. Design A cross-sectional study of asymptomatic …

Image-based consensus molecular subtype (imCMS) classification of colorectal cancer using deep learning

…, A Chatzipli, C Hardy, CM Whalley, C Wu, AD Beggs… - Gut, 2021 - gut.bmj.com
Objective Complex phenotypes captured on histological slides represent the biological
processes at play in individual cancers, but the link to underlying molecular classification has not …

[HTML][HTML] Molecular characterization of colorectal cancer related peritoneal metastatic disease

…, JWM Martens, S Hallam, AD Beggs… - Nature …, 2022 - nature.com
A significant proportion of colorectal cancer (CRC) patients develop peritoneal metastases (PM)
in the course of their disease. PMs are associated with a poor quality of life, significant …

KRAS mutation and consensus molecular subtypes 2 and 3 are independently associated with reduced immune infiltration and reactivity in colorectal cancer

…, G Goussous, O Pickles, MJ Mason, AD Beggs… - Clinical Cancer …, 2018 - AACR
AD Beggs reports receiving other commercial research support from Illumina Inc. No potential
… This article must therefore be hereby marked advertisement in accordance with 18 USC …

Mental health symptoms in a cohort of hospital healthcare workers following the first peak of the COVID-19 pandemic in the UK

…, P Logan, CV Thompson, H Bermingham, AD Beggs… - BJPsych …, 2021 - cambridge.org
BackgroundThe coronavirus disease 2019 (COVID-19) pandemic is likely to lead to a
significant increase in mental health disorders among healthcare workers (HCW).AimsWe …

TERC polymorphisms are associated both with susceptibility to colorectal cancer and with longer telomeres

AM Jones, AD Beggs, L Carvajal-Carmona… - Gut, 2012 - gut.bmj.com
Background and aims Shorter telomeres have been associated with increased risk of
malignancy, including colorectal cancer (CRC). Telomere length is heritable and may be an …