Genomes vary dramatically in size and in content. This variation is driven in part by numerous
polyploidization events that have happened over the course of eukaryotic evolution. …

One of the greatest puzzles in evolutionary biology is the high frequency of sexual reproduction
and recombination. Given that individuals surviving to reproductive age have genomes …

Genome size, a fundamental aspect of any organism, is subject to a variety of mutational
and selection pressures. We investigated genome size evolution in haploid, diploid, and …

Cryptococcus neoformans is a major life-threatening fungal pathogen. In response to the
stress of the host environment, C. neoformans produces large polyploid titan cells. Titan cell …

Tremendous diversity exists among organisms with respect to their ploidy level, defined as
the number of sets of homologous chromosomes per cell. As differences in ploidy represent a …

… Forche A, Cromie G, Gerstein AC et al. Rapid phenotypic and genotypic diversification after
… Gerstein AC. Mutational effects depend on ploidy level: all else is not equal. Biol Lett 2013;9:…

Convergent adaptation occurs at the genome scale when independently evolving lineages
use the same genes to respond to similar selection pressures. These patterns of genetic …

Despite a great deal of theoretical attention, we have limited empirical data about how ploidy
influences the rate of adaptation. We evolved isogenic haploid and diploid populations of …

In vitro studies suggest that stress may generate random standing variation and that different
cellular and ploidy states may evolve more rapidly under stress. Yet this idea has not been …

… At least one functional allele at each of two unlinked loci (Ac and Li) is required to produce
HCN following tissue damage, whereas plants that are homozygous for gene deletions (ac …