Ballgown bridges the gap between transcriptome assembly and expression analysis

AC Frazee, G Pertea, AE Jaffe, B Langmead… - Nature …, 2015 - nature.com
To the Editor: Analysis of raw reads from RNA sequencing (RNA-seq) makes it possible to
reconstruct complete gene structures, including multiple splice variants, without relying on …

Polyester: simulating RNA-seq datasets with differential transcript expression

AC Frazee, AE Jaffe, B Langmead, JT Leek - Bioinformatics, 2015 - academic.oup.com
… Data from the GEUVADIS study is available from the ArrayExpress database (www.ebi.ac.uk/arrayexpress)
under accession numbers E-GEUV-1 through E-GEUV-6. We specifically …

[HTML][HTML] ReCount: a multi-experiment resource of analysis-ready RNA-seq gene count datasets

AC Frazee, B Langmead, JT Leek - BMC bioinformatics, 2011 - Springer
Background RNA sequencing is a flexible and powerful new approach for measuring gene,
exon, or isoform expression. To maximize the utility of RNA sequencing data, new statistical …

Differential expression analysis of RNA-seq data at single-base resolution

AC Frazee, S Sabunciyan, KD Hansen, RA Irizarry… - …, 2014 - academic.oup.com
RNA-sequencing (RNA-seq) is a flexible technology for measuring genome-wide expression
that is rapidly replacing microarrays as costs become comparable. Current differential …

Flexible expressed region analysis for RNA-seq with derfinder

L Collado-Torres, A Nellore, AC Frazee… - Nucleic acids …, 2017 - academic.oup.com
Differential expression analysis of RNA sequencing (RNA-seq) data typically relies on
reconstructing transcripts or counting reads that overlap known gene structures. We previously …

[HTML][HTML] Flexible isoform-level differential expression analysis with Ballgown

AC Frazee, G Pertea, AE Jaffe, B Langmead… - Biorxiv, 2014 - biorxiv.org
We have built a statistical package called Ballgown for estimating differential expression of
genes, transcripts, or exons from RNA sequencing experiments. Ballgown is designed to …

[PDF][PDF] Flexible analysis of transcriptome assemblies with Ballgown

AC Frazee, G Pertea, AE Jaffe, B Langmead… - Biorxiv, 2014 - biorxiv.org
… The authors would like to thank Peter AC ’t Hoen and Tuuli Lappalainen for providing QC
data and assistance with contacting ArrayExpress. JTL, GP, and BL were partially supported by …

derfinder: Software for annotation-agnostic rna-seq differential expression analysis

L Collado-Torres, AC Frazee, MI Love, RA Irizarry… - bioRxiv, 2015 - biorxiv.org
Background Differential expression analysis of RNA sequencing (RNA-seq) data typically
relies on reconstructing transcripts or counting reads that overlap known gene structures. …

Distance functions and attribute weighting in a k-nearest neighbors classifier

AC Frazee, MA Hathcock, SC Bates Prins - 2010 - ecommons.udayton.edu
To assess environmental health of a stream, field, or other ecological object, characteristics
of that object should be compared to a set of reference objects known to be healthy. Using …

Building a research‐community collaborative to improve community care for infants and toddlers at‐risk for autism spectrum disorders

L Brookman‐Frazee, AC Stahmer… - Journal of …, 2012 - Wiley Online Library
This article describes the formation and initial outcomes of a research‐community collaborative
group that was developed based on community‐based participatory research principles. …