Introns can significantly affect gene expression in plants and many other eukaryotes in a
variety of ways. Several types of gene regulation, both positive and negative, that involve plant …

… Lesilee Rose and Derrick Hicks for helpful comments on the manuscript, and Dr. Keith
Bradnam for computational assistance. The authors gratefully acknowledge research support over …

Two classes of sequences in the yeast Saccharomyces cerevisiae are subject to transcriptional
silencing: the silent mating-type cassettes and telomeres. In this report we demonstrate …

Background Alleles of the apolipoprotein E (APOE) gene modulate risk for Alzheimer's disease,
with carriers of the ɛ4 allele being at increased risk and carriers of the ɛ2 allele possibly …

The structural organization of the plasmid (Fig. 1) is integral to its mode of persistence. The
plasmid consists of two unique regions separated by two regions of 599 base pairs (bp) each …

… and Beliakoff, 2000), or in the 3′-UTR 25 or 80 nucleotides downstream of the stop codon
(Rose, 2002). Five new TRP1:GUS fusions were created, each of which contains a single PstI …

… To evaluate a particular parameter set, we ran the IMEter on six experimentally tested
introns (Rose, 2002) and plotted the IMEter scores against the observed level of mRNA …

A picture is beginning to emerge from a variety of organisms that for a subset of genes, the
most important sequences that regulate expression are situated not in the promoter but rather …

Introns in a wide range of organisms including plants, animals and fungi are able to
increase the expression of the gene that they are contained in. This process of intron-mediated …

Objective: To investigate the occurrence of status epilepticus and seizure clusters, and the
duration until first seizure at epilepsy monitoring units in the United States. Methods: The …