Bone marrow mesenchymal stem cells (MSCs) are considered as a promising cell source to
treat the acute myocardial infarction. However, over 90% of the stem cells usually die in the …

Acute myocardial infarction (MI) is the leading cause of death worldwide. Exogenous delivery
of nitric oxide (NO) to the infarcted myocardium has proven to be an effective strategy for …

Dopamine receptor subtypes D 1 and D 2 , and many other seven-transmembrane receptors
including adenosine receptor A 2A , are colocalized in striatum of brain. These receptors …

Wound healing is regulated by a complex series of events and overlapping phases. A
delicate balance of cytokines and mediators in tissue repair is required for optimal therapy in …

Nitric oxide (NO) is a short-lived signaling molecule that plays a pivotal role in cardiovascular
system. Organic nitrates represent a class of NO-donating drugs for treating coronary artery …

There is a lack in clinically-suitable vascular grafts. Biotubes, prepared using in vivo tissue
engineering, show potential for vascular regeneration. However, their mechanical strength is …

In our previous work, we showed for the first time that the voltage-gated proton channel Hv1
is specifically expressed in highly metastatic human breast tumor tissues and cell lines. …

Low cell retention and engraftment after transplantation limit the successful application of
stem cell therapy for AKI. Engineered microenvironments consisting of a hydrogel matrix and …

Bone marrow mesenchymal stem cells (MSCs) have demonstrated their pluripotency to
differentiate into different cell lineages and may be an alternative cell source for vascular tissue …

Gut mucosal layers are crucial in maintaining the gut barrier function. Gut microbiota regulate
homeostasis of gut mucosal layer via gut immune cells such as RORγt (+) IL-22(+) ILC3 …