In this paper, we provide an extensive overview of machine learning techniques applied to
structural magnetic resonance imaging (MRI) data to obtain clinical classifiers. We specifically …

Background Obesity has been linked with subtle differences in brain structure. These
differences tend to be especially relevant in prefrontal cortex regions, areas which play an …

Some Diffusion Tensor Imaging studies have shown a loss of white matter (WM) integrity
linked to impaired cognitive function in obese individuals. However, inconsistent WM integrity …

Parkinson’s disease varies widely in clinical manifestations, course of progression and biomarker
profiles from person to person. Identification of distinct Parkinson’s disease subtypes is …

10.7554/eLife.08440.001 We mapped the distribution of atrophy in Parkinson's disease (PD)
using magnetic resonance imaging (MRI) and clinical data from 232 PD patients and 117 …

Here we test the hypothesis that the neurodegenerative process in Parkinson’s disease (PD)
moves stereotypically along neural networks, possibly reflecting the spread of toxic alpha-…

Recent molecular genetic studies have shown that the majority of genes associated with
obesity are expressed in the central nervous system. Obesity has also been associated with …

… The final sample (n = 20, 12 females) was aged between 18 and 27 y old (mean age ± SD
= 21.60 ± 2.89 y), with an average of 5.24 ± 5.20 y of formal or informal musical training and …

Genes associated with risk for brain disease exhibit characteristic expression patterns that
reflect both anatomical and cell type relationships. Brain-wide transcriptomic patterns of …

Parkinson’s disease varies in severity and age of onset. One source of this variability is sex.
Males are twice as likely as females to develop Parkinson’s disease, and tend to have more …