The goal of this study was to determine which neural elements are excited by microstimulation
of the central nervous system. A cable model of a neuron including an axon, initial …

Objective: To provide an analysis of stimulation parameters for deep brain stimulation (DBS).
Methods: Synthesis of theoretical and empirical findings is used to provide guidance for the …

Deep brain stimulation (DBS) is an effective therapy for medically refractory movement
disorders. However, fundamental questions remain about the effects of DBS on neurons …

Acute experiments were performed on adult cats to study selective activation of medial
gastrocnemius, soleus, tibialis anterior, and extensor digitorium longus with a cuff electrode. A …

The objective of this study was to characterize the tissue response to multiple contact spiral
nerve cuff electrodes implanted on the sciatic nerve of seven cats for 28–34 weeks. The cuffs …

Neural interfaces are connections that enable two-way exchange of information with the
nervous system. These connections can occur at multiple levels, including with peripheral …

Deep brain stimulation (DBS) is a neurosurgical procedure that allows targeted circuit-based
neuromodulation. DBS is a standard of care in Parkinson disease, essential tremor and …

The objective of this project was to examine the influence of stimulus waveform and frequency
on extracellular stimulation of neurons with their cell bodies near the electrode (local cells…

Deep brain stimulation (DBS) is an effective treatment for movement disorders, but the
mechanisms are unclear. DBS generates inhibition of neurons surrounding the electrode while …

The effects of anisotropy and inhomogeneity of the electrical conductivity of extracellular
tissue on excitation of nerve fibers by an extracellular point source electrode were determined …