Emergence and global spread of epidemic healthcare-associated Clostridium difficile
Epidemic C. difficile (027/BI/NAP1) has rapidly emerged in the past decade as the leading
cause of antibiotic-associated diarrhea worldwide. However, the key events in evolutionary …
cause of antibiotic-associated diarrhea worldwide. However, the key events in evolutionary …
Capsular Serotype K1 or K2, Rather than magA and rmpA, Is a Major Virulence Determinant for Klebsiella pneumoniae Liver Abscess in Singapore and Taiwan
KM Yeh, A Kurup, LK Siu, YL Koh… - Journal of clinical …, 2007 - Am Soc Microbiol
Capsular serotypes, magA, and rmpA have been documented in high prevalence for Klebsiella
pneumoniae liver abscess. To investigate the regional difference and the correlation of …
pneumoniae liver abscess. To investigate the regional difference and the correlation of …
Evaluation of Screening Methods To Detect Plasmid-Mediated AmpC in Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis
TY Tan, LSY Ng, J He, TH Koh… - Antimicrobial agents and …, 2009 - Am Soc Microbiol
There are currently no standardized phenotypic methods for the screening and detection of
AmpC enzymes. This study aimed to evaluate different methods to detect AmpC enzymes in …
AmpC enzymes. This study aimed to evaluate different methods to detect AmpC enzymes in …
Molecular typing and virulence analysis of serotype K1 Klebsiella pneumoniae strains isolated from liver abscess patients and stool samples from noninfectious …
…, FY Chang, N Lee, KM Yeh, TH Koh… - Journal of clinical …, 2011 - Am Soc Microbiol
Serotype K1 Klebsiella pneumoniae with multilocus sequence type 23 (ST23) has been
strongly associated with liver abscess in Taiwan. Few data regarding the strain types and …
strongly associated with liver abscess in Taiwan. Few data regarding the strain types and …
[HTML][HTML] Population genomics of hypervirulent Klebsiella pneumoniae clonal-group 23 reveals early emergence and rapid global dissemination
Severe liver abscess infections caused by hypervirulent clonal-group CG23 Klebsiella
pneumoniae have been increasingly reported since the mid-1980s. Strains typically possess …
pneumoniae have been increasingly reported since the mid-1980s. Strains typically possess …
Surveillance and correlation of antibiotic prescription and resistance of Gram-negative bacteria in Singaporean hospitals
A surveillance study was performed in four Singapore public hospitals from 2006 to 2008 to
determine the correlation between antibiotic prescription and Gram-negative bacterial …
determine the correlation between antibiotic prescription and Gram-negative bacterial …
IMP-4 and OXA β-lactamases in Acinetobacter baumannii from Singapore
TH Koh, LH Sng, GCY Wang, LY Hsu… - Journal of antimicrobial …, 2007 - academic.oup.com
Objective To compare the incidence of carbapenemase genes in Acinetobacter baumannii
between two time periods. Methods We studied 114 isolates of imipenem-resistant A. …
between two time periods. Methods We studied 114 isolates of imipenem-resistant A. …
[HTML][HTML] Genotypes and virulence in serotype K2 Klebsiella pneumoniae from liver abscess and non-infectious carriers in Hong Kong, Singapore and Taiwan
JC Lin, TH Koh, N Lee, CP Fung, FY Chang, YK Tsai… - Gut pathogens, 2014 - Springer
In Klebsiella pneumoniae liver abscess (KP-LA), K. pneumonia e K2 is the most frequently
isolated serotype after K1, but this serotype has been much less studied. In the present study, …
isolated serotype after K1, but this serotype has been much less studied. In the present study, …
[HTML][HTML] Evolutionary dynamics of methicillin-resistant Staphylococcus aureus within a healthcare system
…, SR Harris, MA Chlebowicz, JA Lindsay, TH Koh… - Genome Biology, 2015 - Springer
Background In the past decade, several countries have seen gradual replacement of
endemic multi-resistant healthcare-associated methicillin-resistant Staphylococcus aureus (MRSA) …
endemic multi-resistant healthcare-associated methicillin-resistant Staphylococcus aureus (MRSA) …
Occurrences and characterization of antibiotic-resistant bacteria and genetic determinants of hospital wastewater in a tropical country
Wastewater discharged from clinical isolation and general wards at two hospitals in
Singapore was examined to determine the emerging trends of antibiotic resistance (AR). We …
Singapore was examined to determine the emerging trends of antibiotic resistance (AR). We …