User profiles for Tihana Bicanic

Tihana Bicanic

St George's University of London
Verified email at sgul.ac.uk
Cited by 12195

[HTML][HTML] Tackling the emerging threat of antifungal resistance to human health

…, A Alastruey-Izquierdo, J Berman, T Bicanic… - Nature reviews …, 2022 - nature.com
Invasive fungal infections pose an important threat to public health and are an under-recognized
component of antimicrobial resistance, an emerging crisis worldwide. Across a period …

Cryptococcal meningitis

T Bicanic, TS Harrison - British medical bulletin, 2004 - academic.oup.com
Cryptococcal meningitis is a common opportunistic infection in AIDS patients, particularly in
Southeast Asia and Africa. Cases also occur in patients with other forms of …

Cryptococcus: from environmental saprophyte to global pathogen

RC May, NRH Stone, DL Wiesner, T Bicanic… - Nature Reviews …, 2016 - nature.com
Cryptococcosis is a globally distributed invasive fungal infection that is caused by species
within the genus Cryptococcus which presents substantial therapeutic challenges. Although …

[HTML][HTML] The importance of antimicrobial resistance in medical mycology

…, AT Coste, CA Cuomo, DS Perlin, T Bicanic… - Nature …, 2022 - nature.com
Prior to the SARS-CoV-2 pandemic, antibiotic resistance was listed as the major global health
care priority. Some analyses, including the O’Neill report, have predicted that deaths due …

Liposomal Amphotericin B (AmBisome®): A Review of the Pharmacokinetics, Pharmacodynamics, Clinical Experience and Future Directions

NRH Stone, T Bicanic, R Salim, W Hope - Drugs, 2016 - Springer
Liposomal amphotericin B (AmBisome ® ; LAmB) is a unique lipid formulation of amphotericin
B. LAmB is a standard of care for a wide range of medically important opportunistic fungal …

Determinants of mortality in a combined cohort of 501 patients with HIV-associated Cryptococcal meningitis: implications for improving outcomes

JN Jarvis, T Bicanic, A Loyse… - Clinical infectious …, 2014 - academic.oup.com
Background. Cryptococcal meningitis (CM) is a leading cause of death in individuals infected
with human immunodeficiency virus (HIV). Identifying factors associated with mortality …

[PDF][PDF] A blood atlas of COVID-19 defines hallmarks of disease severity and specificity

…, S Beer, G Berridge, A Beveridge, S Bibi, T Bicanic… - Cell, 2022 - cell.com
Treatment of severe COVID-19 is currently limited by clinical heterogeneity and incomplete
description of specific immune biomarkers. We present here a comprehensive multi-omic …

[HTML][HTML] Antifungal combinations for treatment of cryptococcal meningitis in Africa

…, V Sini, YN Mapoure, P Mwaba, T Bicanic… - … England Journal of …, 2018 - Mass Medical Soc
Background Cryptococcal meningitis accounts for more than 100,000 human immunodeficiency
virus (HIV)–related deaths per year. We tested two treatment strategies that could be …

Fungal burden, early fungicidal activity, and outcome in cryptococcal meningitis in antiretroviral-naive or antiretroviral-experienced patients treated with amphotericin …

T Bicanic, G Meintjes, R Wood, M Hayes… - Clinical infectious …, 2007 - academic.oup.com
In a prospective observational study of 54 patients with human immunodeficiency virus–associated
cryptococcal meningitis, the early fungicidal activity of amphotericin B (1 mg/kg/day) …

Adjunctive interferon-γ immunotherapy for the treatment of HIV-associated cryptococcal meningitis: a randomized controlled trial

JN Jarvis, G Meintjes, K Rebe, GN Williams, T Bicanic… - Aids, 2012 - journals.lww.com
Background: Interferon-gamma (IFNγ) is of key importance in the immune response to
Cryptococcus neoformans. Mortality related to cryptococcal meningitis remains high, and novel …