A detailed understanding of the processes governing adipose tissue formation will be
instrumental in combating the obesity epidemic. Much progress has been made in the last two …

Brown adipose tissue (BAT) can disperse stored energy as heat. Promoting BAT-like features
in white adipose (WAT) is an attractive, if elusive, therapeutic approach to staunch the …

The differentiation of 3T3 preadipocytes into adipocytes is accompanied by a transient
induction of C/EBPβ and C/EBPδ expression in response to treatment of the cells with …

Activation of adipogenesis in 3T3 preadipocytes by exposure to the adipogenic inducers
dexamethasone, methylisobutylxanthine, insulin, and fetal bovine serum is accompanied by a …

We demonstrate that exposure of post-confluent 3T3-L1 preadipocytes to insulin,
isobutylmethylxanthine (MIX), dexamethasone (DEX), and fetal bovine serum induces a rapid but …

Freshly isolated adult rat hepatocytes exhibit a flat, extended morphology when cultured on
dried rat tail collagen in the presence of growth factors; they actively synthesize DNA and …

To define the molecular mechanisms that control GLUT4 expression during adipogenesis,
NIH-3T3 fibroblasts ectopically expressing different adipogenic transcription factors (C/…

Recent advances regarding the biology of adipose tissue have identified the adipocyte as
an important mediator in many physiologic and pathologic processes regarding energy …

Peroxisome proliferator-activated receptor-γ (PPARγ) is considered to be one of the master
regulators of adipocyte differentiation. PPARγ2 is abundantly expressed in mature …

Molecular mechanisms coupling growth arrest and cell differentiation were examined during
adipogenesis. Data are presented that document a cascade expression of members of two …