User profiles for Shyam Srinivasan

Shyam Srinivasan

HBNI
Verified email at actrec.gov.in
Cited by 33

Cortical folding: when, where, how, and why?

GF Striedter, S Srinivasan… - Annual review of …, 2015 - annualreviews.org
Why the cerebral cortex folds in some mammals but not in others has long fascinated and
mystified neurobiologists. Over the past century—especially the past decade—researchers …

[HTML][HTML] Redesigning metabolism based on orthogonality principles

AV Pandit, S Srinivasan, R Mahadevan - Nature Communications, 2017 - nature.com
Modifications made during metabolic engineering for overproduction of chemicals have
network-wide effects on cellular function due to ubiquitous metabolic interactions. These …

Predicting visual acuity from the structure of visual cortex

S Srinivasan, CN Carlo… - Proceedings of the …, 2015 - National Acad Sciences
Three decades ago, Rockel et al. proposed that neuronal surface densities (number of
neurons under a square millimeter of surface) of primary visual cortices (V1s) in primates is 2.5 …

[PDF][PDF] Scaling principles of distributed circuits

S Srinivasan, CF Stevens - Current Biology, 2019 - cell.com
Identifying shared quantitative features of a neural circuit across species is important for 3
reasons. Often expressed in the form of power laws and called scaling relationships [1, 2], they …

Constructing kinetic models of metabolism at genome‐scales: a review

S Srinivasan, WR Cluett, R Mahadevan - Biotechnology journal, 2015 - Wiley Online Library
Constraint‐based modeling of biological networks (metabolism, transcription and signal
transduction), although used successfully in many applications, suffer from specific limitations …

Deep (er) learning

S Srinivasan, RJ Greenspan, CF Stevens… - Journal of …, 2018 - Soc Neuroscience
Animals successfully thrive in noisy environments with finite resources. The necessity to
function with resource constraints has led evolution to design animal brains (and bodies) to be …

Metabolic model guided strain design of cyanobacteria

JI Hendry, A Bandyopadhyay, S Srinivasan… - Current opinion in …, 2020 - Elsevier
… Author links open overlay panel John I Hendry 1 , Anindita Bandyopadhyay 2 , Shyam
Srinivasan 1 , Himadri B Pakrasi 2 , Costas D Maranas 1 …

[PDF][PDF] Mechanical strain determines cilia length, motility, and planar position in the left-right organizer

YH Chien, S Srinivasan, R Keller, C Kintner - Developmental cell, 2018 - cell.com
The Xenopus left-right organizer (LRO) breaks symmetry along the left-right axis of the early
embryo by producing and sensing directed ciliary flow as a patterning cue. To carry out this …

The distributed circuit within the piriform cortex makes odor discrimination robust

S Srinivasan, CF Stevens - Journal of Comparative Neurology, 2018 - Wiley Online Library
Distributed circuits wherein connections between subcircuit components seem randomly
distributed are common to the olfactory circuit, hippocampus, and cerebellum. In such circuits, …

Transarterial Chemoembolization (TACE) combined with sorafenib versus TACE in patients with BCLC Stage C hepatocellular carcinoma–a retrospective study

…, K Chandel, NK Condati, SV Srinivasan… - Journal of Clinical and …, 2022 - Elsevier
Objective Advanced-stage hepatocellular carcinoma is a heterogeneous group with limited
treatment options. TACE has been advocated recently by various study groups. The purpose …