[HTML][HTML] Trajectory of IgG to SARS-CoV-2 after vaccination with BNT162b2 or mRNA-1273 in an employee cohort and comparison with natural infection

…, G Canderan, DD Murphy, SG Brovero… - Frontiers in …, 2022 - frontiersin.org
Three COVID-19 vaccines have received FDA-authorization and are in use in the United
States, but there is limited head-to-head data on the durability of the immune response elicited …

Investigation of Drosophila fruitless neurons that express Dpr/DIP cell adhesion molecules

SG Brovero, JC Fortier, H Hu, PC Lovejoy, NR Newell… - Elife, 2021 - elifesciences.org
Drosophila reproductive behaviors are directed by fruitless neurons. A reanalysis of
genomic studies shows that genes encoding dpr and DIP immunoglobulin superfamily (IgSF) …

Single-cell transcriptome profiles of Drosophila fruitless-expressing neurons from both sexes

CM Palmateer, C Artikis, SG Brovero, B Friedman… - Elife, 2023 - elifesciences.org
Drosophila melanogaster reproductive behaviors are orchestrated by fruitless neurons. We
performed single-cell RNA-sequencing on pupal neurons that produce sex-specifically …

[HTML][HTML] Analysis of cell-type-specific chromatin modifications and gene expression in Drosophila neurons that direct reproductive behavior

CM Palmateer, SC Moseley, S Ray, SG Brovero… - Plos …, 2021 - journals.plos.org
Examining the role of chromatin modifications and gene expression in neurons is critical for
understanding how the potential for behaviors are established and maintained. We …

[PDF][PDF] Improved survival of SARS COV-2-infected K18-hACE2 mice treated with adenosine A2AR agonist

BJ Mann, P Chhabra, M Ma, SG Brovero, RT Hannan… - Heliyon, 2023 - cell.com
A life-threatening manifestation of Covid-19 infection is a cytokine storm that requires
hospitalization and supplemental oxygen. Various strategies to reduce inflammatory cytokines …

Neurogenetic and genomic approaches reveal roles for Dpr/DIP cell adhesion molecules in Drosophila reproductive behavior

SG Brovero, JC Fortier, H Hu, PC Lovejoy, NR Newell… - bioRxiv, 2020 - biorxiv.org
Drosophila reproductive behaviors are directed by fruitless neurons (fru P1 isoforms). A
reanalysis of genomic studies shows that genes encoding dpr and DIP Immunoglobulin …

Adenosine A2A Receptor (A2AR) agonists improve survival in K28-hACE2 mice following SARS CoV-2 infection

BJ Mann, P Chhabra, M Ma, SG Brovero, MK Jones… - bioRxiv, 2022 - biorxiv.org
Effective and available therapies for the treatment of COVID-19 disease are limited. Apadenoson
is a highly potent selective anti-inflammatory adenosine A 2A receptor (A 2A R) agonist …

[HTML][HTML] Development of COVID-19 vaccine using a dual Toll-like receptor ligand liposome adjuvant

MM Abhyankar, BJ Mann, JM Sturek, S Brovero… - npj Vaccines, 2021 - nature.com
We developed a SARS-CoV-2 spike subunit vaccine formulation containing dual TLR
ligand liposome adjuvant. The vaccine-induced robust systemic neutralizing antibodies and …

Secondary bile acids function through the vitamin D receptor in myeloid progenitors to promote myelopoiesis

…, J Revilla, MJ Uddin, DN Oakland, S Brovero… - Blood …, 2023 - ashpublications.org
Metabolic products of the microbiota can alter hematopoiesis. However, the contribution and
site of action of bile acids is poorly understood. Here, we demonstrate that the secondary …

Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly

…, AO Pisco, C Reisenman, EN Sanders, G Dos Santos… - Science, 2022 - science.org
For more than 100 years, the fruit fly Drosophila melanogaster has been one of the most
studied model organisms. Here, we present a single-cell atlas of the adult fly, Tabula …