[HTML][HTML] Unique phenotypes and clonal expansions of human CD4 effector memory T cells re-expressing CD45RA

…, V Schulten, VS Patil, G Seumois, SL Rosales… - Nature …, 2017 - nature.com
The expression of CD45RA is generally associated with naive T cells. However, a subset of
effector memory T cells re-expresses CD45RA (termed TEMRA) after antigenic stimulation …

[PDF][PDF] Direct probing of germinal center responses reveals immunological features and bottlenecks for neutralizing antibody responses to HIV Env trimer

…, JS Wood, K Kaushik, MJ van Gils, SL Rosales… - Cell reports, 2016 - cell.com
Generating tier 2 HIV-neutralizing antibody (nAb) responses by immunization remains a
challenging problem, and the immunological barriers to induction of such responses with Env …

Recurrent group A Streptococcus tonsillitis is an immunosusceptibility disease involving antibody deficiency and aberrant TFH cells

…, K Kendric, R Al-Kolla, K Kaushik, SL Rosales… - Science translational …, 2019 - science.org
“Strep throat” is highly prevalent among children, yet it is unknown why only some children
develop recurrent tonsillitis (RT), a common indication for tonsillectomy. To gain insights into …

[HTML][HTML] Cutting edge: transcriptional profiling reveals multifunctional and cytotoxic antiviral responses of Zika virus–specific CD8+ T cells

…, J Pham, Y Tian, SL Rosales… - The Journal of …, 2018 - journals.aai.org
Zika virus (ZIKV) constitutes an increasing public health problem. Previous studies have
shown that CD8+ T cells play an important role in ZIKV-specific protective immunity. We have …

Differential Recognition of Mycobacterium tuberculosis–Specific Epitopes as a Function of Tuberculosis Disease History

…, V Rozot, G Seumois, SL Rosales… - American journal of …, 2017 - atsjournals.org
Rationale: Individuals with a history of tuberculosis (TB) disease are at elevated risk of
disease recurrence. The underlying cause is not known, but one explanation is that previous …

Recurrent group A tonsillitis is an immunosusceptibility disease involving antibody deficiency and aberrant TFH cells

…, R Al-Kolla, K Kaushik, SL Rosales… - Science …, 2019 - eprints.soton.ac.uk
"Strep throat" is highly prevalent among children, yet it is unknown why only some children
develop recurrent tonsillitis (RT), a common indication for tonsillectomy. To gain insights into …

Evidence that recurrent Group A streptococcus tonsillitis is an immunosusceptibility disease involving antibody deficiency and aberrant Tfh cells

…, K Kendric, K Kaushik, SL Rosales… - bioRxiv, 2018 - biorxiv.org
One Sentence Summary Recurrent tonsillitis is a multifactorial disease associated with an
aberrant tonsillar germinal center response to Group A Streptococcus. ABSTRACT Recurrent …

Aqueous enzymatic extraction of Ricinus communis seeds oil using Viscozyme L

P Díaz-Suárez, A Rosales-Quintero… - Industrial Crops and …, 2021 - Elsevier
In this study, the extraction of oil from seeds of castor (Ricinus communis) was intended
using aqueous enzymatic extraction (AEE). After evaluating several enzymes (cellulase, …

A sensitive and integrated approach to profile messenger RNA from samples with low cell numbers

SL Rosales, S Liang, I Engel, BJ Schmiedel… - Type 2 Immunity …, 2018 - Springer
Transcriptomic profiling by RNA sequencing (RNA-Seq) represents the preferred approach
to measure genome-wide gene expression for understanding cellular function, tissue …

[HTML][HTML] Transcriptome and chromatin landscape of iNKT cells are shaped by subset differentiation and antigen exposure

…, G Seumois, S Herrera-De la Mata, SL Rosales… - Nature …, 2021 - nature.com
Invariant natural killer T cells (iNKT cells) differentiate into thymic and peripheral NKT1,
NKT2 and NKT17 subsets. Here we use RNA-seq and ATAC-seq analyses and show iNKT …