User profiles for Rohit Satija
Rohit SatijaGenentech Verified email at gene.com Cited by 354 |
Generalized Langevin equation as a model for barrier crossing dynamics in biomolecular folding
R Satija, DE Makarov - The Journal of Physical Chemistry B, 2019 - ACS Publications
Conformational memory in single-molecule dynamics has attracted recent attention and, in
particular, has been invoked as a possible explanation of some of the intriguing properties of …
particular, has been invoked as a possible explanation of some of the intriguing properties of …
Design of a toolbox of RNA thermometers
Biomolecular temperature sensors can be used for efficient control of large-volume bioreactors,
for spatiotemporal imaging and control of gene expression, and to engineer robustness …
for spatiotemporal imaging and control of gene expression, and to engineer robustness …
[HTML][HTML] Transition path times reveal memory effects and anomalous diffusion in the dynamics of protein folding
Recent single-molecule experiments probed transition paths of biomolecular folding and, in
particular, measured the time biomolecules spend while crossing their free energy barriers. …
particular, measured the time biomolecules spend while crossing their free energy barriers. …
Broad distributions of transition-path times are fingerprints of multidimensionality of the underlying free energy landscapes
R Satija, AM Berezhkovskii… - Proceedings of the …, 2020 - National Acad Sciences
Recent single-molecule experiments have observed transition paths, ie, brief events where
molecules (particularly biomolecules) are caught in the act of surmounting activation barriers. …
molecules (particularly biomolecules) are caught in the act of surmounting activation barriers. …
Transition path times in non-Markovian activated rate processes
E Medina, R Satija, DE Makarov - The Journal of Physical …, 2018 - ACS Publications
Transition paths are brief excursions taken by molecules when they cross barriers separating
stable molecular conformations. When observed in single-molecule experiments, they offer …
stable molecular conformations. When observed in single-molecule experiments, they offer …
Protein turnover dynamics suggest a diffusion-to-capture mechanism for peri-basal body recruitment and retention of intraflagellar transport proteins
JVK Hibbard, N Vazquez, R Satija… - Molecular biology of …, 2021 - Am Soc Cell Biol
Intraflagellar transport (IFT) is essential for construction and maintenance of cilia. IFT proteins
concentrate at the basal body where they are thought to assemble into trains and bind …
concentrate at the basal body where they are thought to assemble into trains and bind …
[HTML][HTML] Theoretical and computational validation of the Kuhn barrier friction mechanism in unfolded proteins
A long time ago, Kuhn predicted that long polymers should approach a limit where their global
motion is controlled by solvent friction alone, with ruggedness of their energy landscapes …
motion is controlled by solvent friction alone, with ruggedness of their energy landscapes …
Transition path dynamics of a dielectric particle in a bistable optical trap
Many processes in chemistry, physics, and biology involve rare events in which the system
escapes from a metastable state by surmounting an activation barrier. Examples range from …
escapes from a metastable state by surmounting an activation barrier. Examples range from …
Kinetics of loop closure in disordered proteins: Theory vs simulations vs experiments
We study intrachain dynamics of intrinsically disordered proteins, as manifested by the time
scales of loop formation, using atomistic simulations, experiment-parametrized coarse-…
scales of loop formation, using atomistic simulations, experiment-parametrized coarse-…
[BOOK][B] Understanding structural transitions and dynamics in biomolecules at a single molecule level
R Satija - 2020 - search.proquest.com
… Rohit Satija 2020 … The Dissertation Committee for Rohit Satija Certifies that this is the approved
… I would also like to thank my very supportive family Bhumika, Lajvanti, and Yograj Satija, …
… I would also like to thank my very supportive family Bhumika, Lajvanti, and Yograj Satija, …