User profiles for Roberto C. Sotero

Roberto C Sotero

Associate Professor at University of Calgary
Verified email at ucalgary.ca
Cited by 3302

Studying the human brain anatomical network via diffusion-weighted MRI and Graph Theory

Y Iturria-Medina, RC Sotero, EJ Canales-Rodríguez… - Neuroimage, 2008 - Elsevier
Our goal is to study the human brain anatomical network. For this, the anatomical connection
probabilities (ACP) between 90 cortical and subcortical brain gray matter areas are …

Realistically coupled neural mass models can generate EEG rhythms

RC Sotero, NJ Trujillo-Barreto… - Neural …, 2007 - ieeexplore.ieee.org
We study the generation of EEG rhythms by means of realistically coupled neural mass
models. Previous neural mass models were used to model cortical voxels and the thalamus. …

Biophysical model for integrating neuronal activity, EEG, fMRI and metabolism

RC Sotero, NJ Trujillo-Barreto - Neuroimage, 2008 - Elsevier
Our goal is to model the coupling between neuronal activity, cerebral metabolic rates of
glucose and oxygen consumption, cerebral blood flow (CBF), electroencephalography (EEG) …

Multifactorial causal model of brain (dis) organization and therapeutic intervention: Application to Alzheimer's disease

Y Iturria-Medina, FM Carbonell, RC Sotero… - Neuroimage, 2017 - Elsevier
Generative models focused on multifactorial causal mechanisms in brain disorders are
scarce and generally based on limited data. Despite the biological importance of the multiple …

Modelling the role of excitatory and inhibitory neuronal activity in the generation of the BOLD signal

RC Sotero, NJ Trujillo-Barreto - Neuroimage, 2007 - Elsevier
A biophysical model of the coupling between neuronal activity and the BOLD signal that
allows for explicitly evaluating the role of both excitatory and inhibitory activity is formulated in …

Measuring transient phase-amplitude coupling using local mutual information

…, J Heng, A Delorme, K Kreutz-Delgado, RC Sotero… - NeuroImage, 2019 - Elsevier
Here we demonstrate the suitability of a local mutual information measure for estimating the
temporal dynamics of cross-frequency coupling (CFC) in brain electrophysiological signals. …

[HTML][HTML] Early role of vascular dysregulation on late-onset Alzheimer's disease based on multifactorial data-driven analysis

Y Iturria-Medina, RC Sotero, PJ Toussaint… - Nature …, 2016 - nature.com
Multifactorial mechanisms underlying late-onset Alzheimer’s disease (LOAD) are poorly
characterized from an integrative perspective. Here spatiotemporal alterations in brain amyloid-…

Model driven EEG/fMRI fusion of brain oscillations

…, JM Sanchez‐Bornot, RC Sotero… - Human brain …, 2009 - Wiley Online Library
This article reviews progress and challenges in model driven EEG/fMRI fusion with a focus
on brain oscillations. Fusion is the combination of both imaging modalities based on a …

[HTML][HTML] Epidemic spreading model to characterize misfolded proteins propagation in aging and associated neurodegenerative disorders

Y Iturria-Medina, RC Sotero, PJ Toussaint… - PLoS computational …, 2014 - journals.plos.org
Misfolded proteins (MP) are a key component in aging and associated neurodegenerative
disorders. For example, misfolded Amyloid-ß (Aß) and tau proteins are two neuropathogenic …

[HTML][HTML] Topological properties of resting-state fMRI functional networks improve machine learning-based autism classification

A Kazeminejad, RC Sotero - Frontiers in neuroscience, 2019 - frontiersin.org
Automatic algorithms for disease diagnosis are being thoroughly researched for use in
clinical settings. They usually rely on pre-identified biomarkers to highlight the existence of …