User profiles for Renwick C.J. Dobson
Renwick CJ DobsonProfessor of Chemical Biology, School of Biological Sciences, University of Canterbury Verified email at canterbury.ac.nz Cited by 19657 |
[HTML][HTML] The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism
…, EC Hatchell, IJ Majewski, T Okamoto, RCJ Dobson… - Immunity, 2013 - cell.com
Mixed lineage kinase domain-like (MLKL) is a component of the "necrosome," the multiprotein
complex that triggers tumor necrosis factor (TNF)-induced cell death by necroptosis. To …
complex that triggers tumor necrosis factor (TNF)-induced cell death by necroptosis. To …
Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death
…, C Pierotti, JM Garnier, RCJ Dobson… - Proceedings of the …, 2014 - National Acad Sciences
Necroptosis is considered to be complementary to the classical caspase-dependent programmed
cell death pathway, apoptosis. The pseudokinase Mixed Lineage Kinase Domain-Like …
cell death pathway, apoptosis. The pseudokinase Mixed Lineage Kinase Domain-Like …
[HTML][HTML] A three-ring circus: metabolism of the three proteogenic aromatic amino acids and their role in the health of plants and animals
A Parthasarathy, PJ Cross, RCJ Dobson… - Frontiers in molecular …, 2018 - frontiersin.org
Tyrosine, phenylalanine and tryptophan are the three aromatic amino acids (AAA) involved
in protein synthesis. These amino acids and their metabolism are linked to the synthesis of a …
in protein synthesis. These amino acids and their metabolism are linked to the synthesis of a …
Fermentation of plant‐based dairy alternatives by lactic acid bacteria
AR Harper, RCJ Dobson, VK Morris… - Microbial …, 2022 - Wiley Online Library
Ethical, environmental and health concerns around dairy products are driving a fast‐growing
industry for plant‐based dairy alternatives, but undesirable flavours and textures in …
industry for plant‐based dairy alternatives, but undesirable flavours and textures in …
[PDF][PDF] Bovine β-lactoglobulin is dimeric under imitative physiological conditions: dissociation equilibrium and rate constants over the pH range of 2.5–7.5
The oligomerization of β-lactoglobulin (βLg) has been studied extensively, but with somewhat
contradictory results. Using analytical ultracentrifugation in both sedimentation equilibrium …
contradictory results. Using analytical ultracentrifugation in both sedimentation equilibrium …
[HTML][HTML] Potential for bacteriophage endolysins to supplement or replace antibiotics in food production and clinical care
There is growing concern about the emergence of bacterial strains showing resistance to all
classes of antibiotics commonly used in human medicine. Despite the broad range of …
classes of antibiotics commonly used in human medicine. Despite the broad range of …
Structural and functional analysis of the GABARAP interaction motif (GIM)
Through the canonical LC3 interaction motif (LIR), [W/F/Y]‐X 1 ‐X 2 ‐[I/L/V], protein complexes
are recruited to autophagosomes to perform their functions as either autophagy adaptors …
are recruited to autophagosomes to perform their functions as either autophagy adaptors …
Genome-wide binding and mechanistic analyses of Smchd1-mediated epigenetic regulation
…, PE Czabotar, RCJ Dobson… - Proceedings of the …, 2015 - National Acad Sciences
Structural maintenance of chromosomes flexible hinge domain containing 1 (Smchd1) is an
epigenetic repressor with described roles in X inactivation and genomic imprinting, but …
epigenetic repressor with described roles in X inactivation and genomic imprinting, but …
[HTML][HTML] The quest for novel antimicrobial compounds: emerging trends in research, development, and technologies
Pathogenic antibiotic resistant bacteria pose one of the most important health challenges of
the 21st century. The overuse and abuse of antibiotics coupled with the natural evolutionary …
the 21st century. The overuse and abuse of antibiotics coupled with the natural evolutionary …
[PDF][PDF] Structural basis of the autophagy-related LC3/Atg13 LIR complex: recognition and interaction mechanism
…, K Tabata, E Morita, M Kawasaki, R Kato, RCJ Dobson… - Structure, 2014 - cell.com
Autophagy is a bulk degradation pathway that removes cytosolic materials to maintain cellular
homeostasis. The autophagy-related gene 13 (Atg13) and microtubule associate protein 1 …
homeostasis. The autophagy-related gene 13 (Atg13) and microtubule associate protein 1 …