Hfq and other Sm proteins are central in RNA metabolism, forming an evolutionarily
conserved family that plays key roles in RNA processing in organisms ranging from archaea to …

We present solid-state NMR measurements of β-strand secondary structure and inter-strand
organization within a 150-kDa oligomeric aggregate of the 42-residue variant of the …

Advances in electron detection have been essential to the success of high-resolution cryo-EM
structure determination. A new generation of direct electron detector called the Apollo, has …

The host factor Hfq, as the bacterial branch of the Sm family, is an RNA-binding protein
involved in the post-transcriptional regulation of mRNA expression and turnover. Hfq facilitates …

Transcription of the human calcitonin (CT) gene is markedly increased by cAMP in the TT
line of medullary thyroid carcinoma. This response is conferred by 5′ flanking DNA …

Previous reports revealed that sodium dodecyl sulfate near its critical micelle concentration
can drive the assembly of Aβ42 along an oligomeric pathway. This pathway produces a 150 …

In cryogenic electron microscopy (cryo-EM), specimen preparation remains a bottleneck
despite recent advancements. Classical plunge freezing methods often result in issues like …

As the field of electron microscopy advances, the increasing complexity of samples being
produced demand more involved processing methods. In this study, we have developed a new …

In cryogenic electron microscopy (cryo-EM), specimen preparation remains a bottleneck
despite recent advancements. Classical plunge freezing methods often result in issues like …

Precursor molecules for biomass incorporation must be imported into cells and made available
to the molecular machines that build the cell. Sulfur-containing macromolecules require …