User profiles for Peter Kraft
 | Peter KraftHarvard TH Chan School of Public Health Verified email at hsph.harvard.edu Cited by 114146 |
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
By combining genome-wide association data from 8,130 individuals with type 2 diabetes (T2D)
and 38,987 controls of European descent and following up previously unidentified meta-…
and 38,987 controls of European descent and following up previously unidentified meta-…
Hundreds of variants clustered in genomic loci and biological pathways affect human height
Most common human traits and diseases have a polygenic pattern of inheritance: DNA
sequence variants at many genetic loci influence the phenotype. Genome-wide association (GWA…
sequence variants at many genetic loci influence the phenotype. Genome-wide association (GWA…
A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer
We conducted a genome-wide association study (GWAS) of breast cancer by genotyping
528,173 SNPs in 1,145 postmenopausal women of European ancestry with invasive breast …
528,173 SNPs in 1,145 postmenopausal women of European ancestry with invasive breast …
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution
Waist-hip ratio (WHR) is a measure of body fat distribution and a predictor of metabolic
consequences independent of overall adiposity. WHR is heritable, but few genetic variants …
consequences independent of overall adiposity. WHR is heritable, but few genetic variants …
Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses
Very few genetic variants have been associated with depression and neuroticism, likely
because of limitations on sample size in previous studies. Subjective well-being, a phenotype …
because of limitations on sample size in previous studies. Subjective well-being, a phenotype …
Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use
…, MC Keller, M Kellis, C Kooperberg, P Kraft… - Nature …, 2019 - nature.com
Tobacco and alcohol use are leading causes of mortality that influence risk for many complex
diseases and disorders 1 . They are heritable 2 , 3 and etiologically related 4 , 5 behaviors …
diseases and disorders 1 . They are heritable 2 , 3 and etiologically related 4 , 5 behaviors …
Genome-wide association study of prostate cancer identifies a second risk locus at 8q24
Recently, common variants on human chromosome 8q24 were found to be associated with
prostate cancer risk. While conducting a genome-wide association study in the Cancer …
prostate cancer risk. While conducting a genome-wide association study in the Cancer …
[HTML][HTML] Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts
Background Obesity is associated with vitamin D deficiency, and both are areas of active
public health concern. We explored the causality and direction of the relationship between …
public health concern. We explored the causality and direction of the relationship between …
Multiple loci identified in a genome-wide association study of prostate cancer
We followed our initial genome-wide association study (GWAS) of 527,869 SNPs on 1,172
individuals with prostate cancer and 1,157 controls of European origin—nested in the Prostate…
individuals with prostate cancer and 1,157 controls of European origin—nested in the Prostate…
An expanded genome-wide association study of type 2 diabetes in Europeans
To characterize type 2 diabetes (T2D)-associated variation across the allele frequency spectrum,
we conducted a meta-analysis of genome-wide association data from 26,676 T2D case …
we conducted a meta-analysis of genome-wide association data from 26,676 T2D case …