Evidence in the Legionella pneumophila genome for exploitation of host cell functions and high genome plasticity

C Cazalet, C Rusniok, H Brüggemann, N Zidane… - Nature …, 2004 - nature.com
Legionella pneumophila, the causative agent of Legionnaires' disease, replicates as an
intracellular parasite of amoebae and persists in the environment as a free-living microbe. Here …

Comparative genomic and phylogeographic analysis of Mycobacterium leprae

M Monot, N Honoré, T Garnier, N Zidane, D Sherafi… - Nature …, 2009 - nature.com
Reductive evolution and massive pseudogene formation have shaped the 3.31-Mb genome
of Mycobacterium leprae, an unculturable obligate pathogen that causes leprosy in humans. …

[HTML][HTML] Genome Sequence of the Saprophyte Leptospira biflexa Provides Insights into the Evolution of Leptospira and the Pathogenesis of Leptospirosis

…, DM Bulach, C Bouchier, RL Zuerner, N Zidane… - PloS one, 2008 - journals.plos.org
Leptospira biflexa is a free-living saprophytic spirochete present in aquatic environments. We
determined the genome sequence of L. biflexa, making it the first saprophytic Leptospira to …

[HTML][HTML] Genetic adaptation and Neandertal admixture shaped the immune system of human populations

…, J Pothlichet, YHE Loh, M Dannemann, N Zidane… - Cell, 2016 - cell.com
Humans differ in the outcome that follows exposure to life-threatening pathogens, yet the
extent of population differences in immune responses and their genetic and evolutionary …

[HTML][HTML] Analysis of the Legionella longbeachae Genome and Transcriptome Uncovers Unique Strategies to Cause Legionnaires' Disease

…, HJ Newton, FM Sansom, S Jarraud, N Zidane… - PLoS …, 2010 - journals.plos.org
Legionella pneumophila and L. longbeachae are two species of a large genus of bacteria
that are ubiquitous in nature. L. pneumophila is mainly found in natural and artificial water …

Genome Sequence of Streptococcus gallolyticus: Insights into Its Adaptation to the Bovine Rumen and Its Ability To Cause Endocarditis

…, E Couvé, V Da Cunha, R El Gana, N Zidane… - Journal of …, 2010 - Am Soc Microbiol
Streptococcus gallolyticus (formerly known as Streptococcus bovis biotype I) is an increasing
cause of endocarditis among streptococci and frequently associated with colon cancer. S. …

[HTML][HTML] Exploring the genetic basis of human population differences in DNA methylation and their causal impact on immune gene regulation

LT Husquin, M Rotival, M Fagny, H Quach, N Zidane… - Genome biology, 2018 - Springer
Background DNA methylation is influenced by both environmental and genetic factors and
is increasingly thought to affect variation in complex traits and diseases. Yet, the extent of …

Genome sequence of Vibrio splendidus: an abundant planctonic marine species with a large genotypic diversity

…, D Saulnier, C Bouchier, N Zidane… - Environmental …, 2009 - Wiley Online Library
Vibrio splendidus is a dominant Vibrio species in seawater presenting a remarkable genetic
diversity; several strains have been linked to invertebrate's mortality. We report the complete …

[HTML][HTML] Ongoing diphtheria outbreak in Yemen: a cross-sectional and genomic epidemiology study

…, M Hennart, A Carmi-Leroy, N Zidane… - The Lancet …, 2021 - thelancet.com
Background An outbreak of diphtheria, declared in Yemen in October, 2017, is ongoing. We
did a cross-sectional study to investigate the epidemiological, clinical, and microbiological …

[PDF][PDF] Signatures of purifying and local positive selection in human miRNAs

H Quach, LB Barreiro, G Laval, N Zidane… - The American Journal of …, 2009 - cell.com
MicroRNAs (miRNAs) are noncoding RNAs involved in posttranscriptional gene repression,
and their role in diverse physiological processes is increasingly recognized. Yet, few efforts …