Although survival has improved in recent years, the prognosis of patients with advanced
pancreatic ductal adenocarcinoma (PDAC) remains poor. Despite substantial differences in …

3075 Background: Proliferation of CD8 T cells can be detected in the blood of cancer patients
(pts) following a single dose of immune checkpoint blockade (ICB) and tends to be more …

Immunotherapy against cancer has shown increased overall survival of metastatic cancer
patients and is a promising new vaccine target. For this to succeed, appropriate tailoring of …

Novel regulators of CD8+ T-cell functions in the skin Page 1 General rights Copyright and moral
rights for the publications made accessible in the public portal are retained by the authors and/or …

Immune therapy of cancer has recently experienced a great breakthrough with prolonged
overall survival in patients with metastatic disease following the use of checkpoint inhibitors …

… Overgaard, Nana Haahr; Frøsig, Thomas Mørch; Welner, Simon; Rasmussen, Michael;
Jakobsen, Jeanne Toft; Ilsøe, Mette; Sørensen, Maria Rathmann; Andersen, Mads H.; Buus …

Established memory T-cell responses represent a key hurdle to protein and tissue
replacement therapies as well as the application of tolerogenic immunotherapies in general. …

Uncovering new pathways of CD8 T-cell regulation in the skin Page 1 General rights
Copyright and moral rights for the publications made accessible in the public portal are …

Quantitative and qualitative assessment of antigen-specific cytotoxic T cell (CTL) responses
in pigs is not a straightforward process. Through the years we have developed a series of …

The immune system plays a crucial role in cancer development and progression. Cancer
immunoediting encompasses three phases: elimination, equilibrium, and escape; together, …