Plant flavonoids: Classification, distribution, biosynthesis, and antioxidant activity
N Shen, T Wang, Q Gan, S Liu, L Wang, B Jin - Food chemistry, 2022 - Elsevier
Flavonoids are a group of natural polyphenol substances abundant in vegetables, fruits,
grains, and tea. As plant secondary metabolites, flavonoids play essential roles in many …
grains, and tea. As plant secondary metabolites, flavonoids play essential roles in many …
Partial restoration of the microbiota of cesarean-born infants via vaginal microbial transfer
MG Dominguez-Bello, KM De Jesus-Laboy, N Shen… - Nature medicine, 2016 - nature.com
Exposure of newborns to the maternal vaginal microbiota is interrupted with cesarean birthing.
Babies delivered by cesarean section (C-section) acquire a microbiota that differs from …
Babies delivered by cesarean section (C-section) acquire a microbiota that differs from …
[PDF][PDF] Structure and degradation of circular RNAs regulate PKR activation in innate immunity
Circular RNAs (circRNAs) produced from back-splicing of exons of pre-mRNAs are widely
expressed, but current understanding of their functions is limited. These RNAs are stable in …
expressed, but current understanding of their functions is limited. These RNAs are stable in …
Targeting interleukin-6 in inflammatory autoimmune diseases and cancers
X Yao, J Huang, H Zhong, N Shen, R Faggioni… - Pharmacology & …, 2014 - Elsevier
Interleukin-6 (IL-6) is a pleiotropic cytokine with significant functions in the regulation of the
immune system. As a potent pro-inflammatory cytokine, IL-6 plays a pivotal role in host …
immune system. As a potent pro-inflammatory cytokine, IL-6 plays a pivotal role in host …
The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-α
Inflammatory cytokines such as interleukin-17 (IL-17) promote inflammatory autoimmune
diseases. Although several microRNAs (miRNAs) have been shown to regulate autoimmune …
diseases. Although several microRNAs (miRNAs) have been shown to regulate autoimmune …
The microbiome in early life: implications for health outcomes
Recent studies have characterized how host genetics, prenatal environment and delivery
mode can shape the newborn microbiome at birth. Following this, postnatal factors, such as …
mode can shape the newborn microbiome at birth. Following this, postnatal factors, such as …
MicroRNA‐146a contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins
Objective MicroRNA have recently been identified as regulators that modulate target gene
expression and are involved in shaping the immune response. This study was undertaken to …
expression and are involved in shaping the immune response. This study was undertaken to …
The microbiome of uncontacted Amerindians
Most studies of the human microbiome have focused on westernized people with life-style
practices that decrease microbial survival and transmission, or on traditional societies that are …
practices that decrease microbial survival and transmission, or on traditional societies that are …
MicroRNA-21 and microRNA-148a contribute to DNA hypomethylation in lupus CD4+ T cells by directly and indirectly targeting DNA methyltransferase 1
Systemic lupus erythematosus is a complex autoimmune disease caused by genetic and
epigenetic alterations. DNA methylation abnormalities play an important role in systemic lupus …
epigenetic alterations. DNA methylation abnormalities play an important role in systemic lupus …
Selenium–GPX4 axis protects follicular helper T cells from ferroptosis
Follicular helper T (T FH ) cells are a specialized subset of CD4 + T cells that essentially
support germinal center responses where high-affinity and long-lived humoral immunity is …
support germinal center responses where high-affinity and long-lived humoral immunity is …