[HTML][HTML] Connecting structure to function with the recovery of over 1000 high-quality metagenome-assembled genomes from activated sludge using long-read …

…, Z Kondrotaite, SM Karst, MS Dueholm… - Nature …, 2021 - nature.com
Microorganisms play crucial roles in water recycling, pollution removal and resource recovery
in the wastewater industry. The structure of these microbial communities is increasingly …

Functional amyloid in Pseudomonas

MS Dueholm, SV Petersen, M Sønderkær… - Molecular …, 2010 - Wiley Online Library
Amyloids are highly abundant in many microbial biofilms and may play an important role in
their architecture. Nevertheless, little is known of the amyloid proteins. We report the …

Retrieval of a million high-quality, full-length microbial 16S and 18S rRNA gene sequences without primer bias

SM Karst, MS Dueholm, SJ McIlroy… - Nature …, 2018 - nature.com
Small subunit ribosomal RNA (SSU rRNA) genes, 16S in bacteria and 18S in eukaryotes,
have been the standard phylogenetic markers used to characterize microbial diversity and …

[HTML][HTML] Culture-independent analyses reveal novel anaerolineaceae as abundant primary fermenters in anaerobic digesters treating waste activated sludge

SJ McIlroy, RH Kirkegaard, MS Dueholm… - Frontiers in …, 2017 - frontiersin.org
Anaerobic digestion for biogas production is reliant on the tightly coupled synergistic
activities of complex microbial consortia. Members of the uncultured A6 phylotype, within the …

[HTML][HTML] Functional bacterial amyloid increases Pseudomonas biofilm hydrophobicity and stiffness

G Zeng, BS Vad, MS Dueholm, G Christiansen… - Frontiers in …, 2015 - frontiersin.org
The success of Pseudomonas species as opportunistic pathogens derives in great part from
their ability to form stable biofilms that offer protection against chemical and mechanical …

[HTML][HTML] The impact of immigration on microbial community composition in full-scale anaerobic digesters

…, JM Kristensen, M Nierychlo, SM Karst, MS Dueholm… - Scientific reports, 2017 - nature.com
Anaerobic digestion is widely applied to treat organic waste at wastewater treatment plants.
Characterisation of the underlying microbiology represents a source of information to …

Expression of Fap amyloids in Pseudomonas aeruginosa, P. fluorescens, and P. putida results in aggregation and increased biofilm formation

MS Dueholm, MT Søndergaard, M Nilsson… - …, 2013 - Wiley Online Library
The fap operon, encoding functional amyloids in P seudomonas (Fap), is present in most
pseudomonads, but so far the expression and importance for biofilm formation has only been …

[HTML][HTML] Curli functional amyloid systems are phylogenetically widespread and display large diversity in operon and protein structure

MS Dueholm, M Albertsen, D Otzen, PH Nielsen - PloS one, 2012 - journals.plos.org
Escherichia coli and a few other members of the Enterobacteriales can produce functional
amyloids known as curli. These extracellular fibrils are involved in biofilm formation and …

On the evolution and physiology of cable bacteria

…, T Yang, MS Dueholm, S Larsen… - Proceedings of the …, 2019 - National Acad Sciences
Cable bacteria of the family Desulfobulbaceae form centimeter-long filaments comprising
thousands of cells. They occur worldwide in the surface of aquatic sediments, where they …

Fibrillation of the major curli subunit CsgA under a wide range of conditions implies a robust design of aggregation

MS Dueholm, SB Nielsen, KL Hein, P Nissen… - Biochemistry, 2011 - ACS Publications
The amyloid fold is usually considered a result of protein misfolding. However, a number of
studies have recently shown that the amyloid structure is also used in nature for functional …