Neutrophils, the most abundant type of leukocytes in blood, can form neutrophil extracellular
traps (NETs). These are pathogen-trapping structures generated by expulsion of the …

CC chemokine receptor type 2 (CCR2) is expressed on monocytes and facilitates their
recruitment to tumors. Though breast cancer cells also express CCR2, its functions in these cells …

The prognosis of metastatic cancer in patients is poor. Interfering with metastatic spread is
therefore important for achieving better survival from cancer. Metastatic disease is established …

Immune checkpoint inhibitor (ICI) therapies used to treat cancer, such as anti–PD-1
antibodies, can induce autoimmune conditions in some individuals. The T cell mechanisms …

… Mantel, Ian; Fein, Miriam R.; Donlin, Laura T. … Keir LS, Firth R, Aponik L, et al. VEGF
regulates local inhibitory complement proteins in the eye and kidney. J Clin Invest 2017; 127:199–214 …

We have utilized the persistent elevation of fractional excretion (FE) of urate,> 10%, to
differentiate cerebral/renal salt wasting (RSW) from the syndrome of inappropriate antidiuretic …

Flow cytometry is a popular laser-based technology that allows the phenotypic and functional
characterization of individual cells in a high-throughput manner. Here, we describe a …

CC chemokine receptor type 2 (CCR2) is highly expressed in human breast cancer tissue by
both cancer cells and infiltrating immune cells. High expression of CCR2 is correlated with …

Intravital imaging can provide unique insights into cancer biology and has been particularly
useful for research into therapy responses, metastasis, and immune responses. Here, we …

We have utilized the persistent elevation of fractional excretion (FE) of urate,> 10%, to
differentiate cerebral/renal salt wasting (RSW) from the syndrome of inappropriate antidiuretic …