Molecular genetic studies of Drosophila melanogaster have led to profound advances in
understanding the regulation of development. Here we report gene expression patterns for …

The steroid hormone 20-hydroxyecdysone coordinates the stages of Drosophila development
by activating a nuclear receptor heterodimer consisting of the ecdysone receptor, EcR, …

Almost every animal lineage is characterized by unique sex-specific traits, implying that
such traits are gained and lost frequently in evolution. However, the genetic mechanisms …

In Drosophila melanogaster few methods exist to perform rapid cell-type or tissue-specific
expression profiling. A translating ribosome affinity purification (TRAP) method to profile …

doublesex (dsx) encodes sex-specific transcription factors (DSX F in females and DSX M in
males) that act at the bottom of the Drosophila somatic sex determination hierarchy. dsx, …

The Drosophila sex determination hierarchy controls all aspects of somatic sexual differentiation,
including sex-specific differences in adult morphology and behavior. To gain insight …

Motivation: Gene expression variation can often be linked to certain chromosomal regions
and are tightly associated with phenotypic variation such as disease conditions. Inferring the …

In virtually all animals, males and females are morphologically,physiologically and behaviorally
distinct. Using cDNA microarrays representing one-third of Drosophila genes to identify …

Background Understanding animal development and physiology at a molecular-biological
level has been advanced by the ability to determine at high resolution the repertoire of mRNA …

Background Drosophila melanogaster adult males perform an elaborate courtship ritual to
entice females to mate. fruitless (fru), a gene that is one of the key regulators of male courtship …