User profiles for Mary Gehring
 | Mary GehringWhitehead Institute for Biomedical Research Verified email at wi.mit.edu Cited by 8385 |
Genome-wide analysis of Arabidopsis thaliana DNA methylation uncovers an interdependence between methylation and transcription
D Zilberman, M Gehring, RK Tran, T Ballinger… - Nature …, 2007 - nature.com
Cytosine methylation, a common form of DNA modification that antagonizes transcription, is
found at transposons and repeats in vertebrates, plants and fungi. Here we have mapped …
found at transposons and repeats in vertebrates, plants and fungi. Here we have mapped …
Extensive demethylation of repetitive elements during seed development underlies gene imprinting
M Gehring, KL Bubb, S Henikoff - Science, 2009 - science.org
DNA methylation is an epigenetic mark associated with transposable element silencing and
gene imprinting in flowering plants and mammals. In plants, imprinting occurs in the …
gene imprinting in flowering plants and mammals. In plants, imprinting occurs in the …
[HTML][HTML] DEMETER, a DNA glycosylase domain protein, is required for endosperm gene imprinting and seed viability in Arabidopsis
We isolated mutations in Arabidopsis to understand how the female gametophyte controls
embryo and endosperm development. For the DEMETER (DME) gene, seed viability depends …
embryo and endosperm development. For the DEMETER (DME) gene, seed viability depends …
[HTML][HTML] Ten things you should know about transposable elements
Transposable elements (TEs) are major components of eukaryotic genomes. However, the
extent of their impact on genome evolution, function, and disease remain a matter of intense …
extent of their impact on genome evolution, function, and disease remain a matter of intense …
DNA demethylation by DNA repair
Active DNA demethylation underlies key facets of reproduction in flowering plants and
mammals and serves a general genome housekeeping function in plants. A family of 5-…
mammals and serves a general genome housekeeping function in plants. A family of 5-…
[HTML][HTML] DEMETER DNA glycosylase establishes MEDEA polycomb gene self-imprinting by allele-specific demethylation
MEDEA (MEA) is an Arabidopsis Polycomb group gene that is imprinted in the endosperm.
The maternal allele is expressed and the paternal allele is silent. MEA is controlled by …
The maternal allele is expressed and the paternal allele is silent. MEA is controlled by …
DNA methylation dynamics in plant genomes
M Gehring, S Henikoff - Biochimica et Biophysica Acta (BBA)-Gene …, 2007 - Elsevier
Cytosine bases are extensively methylated in the DNA of plant genomes. DNA methylation
has been implicated in the silencing of transposable elements and genes, and loss of …
has been implicated in the silencing of transposable elements and genes, and loss of …
[HTML][HTML] Genomic Analysis of Parent-of-Origin Allelic Expression in Arabidopsis thaliana Seeds
M Gehring, V Missirian, S Henikoff - PloS one, 2011 - journals.plos.org
Differential expression of maternally and paternally inherited alleles of a gene is referred to
as gene imprinting, a form of epigenetic gene regulation common to flowering plants and …
as gene imprinting, a form of epigenetic gene regulation common to flowering plants and …
Parent-of-origin effects on gene expression and DNA methylation in the maize endosperm
Imprinting describes the differential expression of alleles based on their parent of origin.
Deep sequencing of RNAs from maize (Zea mays) endosperm and embryo tissue 14 d after …
Deep sequencing of RNAs from maize (Zea mays) endosperm and embryo tissue 14 d after …
[HTML][HTML] Imprinting of the MEA Polycomb gene is controlled by antagonism between MET1 methyltransferase and DME glycosylase
W Xiao, M Gehring, Y Choi, L Margossian, H Pu… - Developmental cell, 2003 - cell.com
The MEA Polycomb gene is imprinted in the Arabidopsis endosperm. DME DNA glycosylase
activates maternal MEA allele expression in the central cell of the female gametophyte, the …
activates maternal MEA allele expression in the central cell of the female gametophyte, the …