Background Fast-food consumption has increased greatly in the USA during the past three
decades. However, the effect of fast food on risk of obesity and type 2 diabetes has received …

ContextComponents of the insulin resistance syndrome (IRS), including obesity, glucose
intolerance, hypertension, and dyslipidemia, are major risk factors for type 2 diabetes and heart …

ContextDietary composition may affect insulin secretion, and high insulin levels, in turn, may
increase the risk for cardiovascular disease (CVD).ObjectiveTo examine the role of fiber …

The BRAF V600E mutation has been associated with microsatellite instability and the CpG
island methylator phenotype (CIMP) in colon cancer. We evaluated a large population-based …

Background: Colorectal cancer is a major public health problem in both North America and
western Europe, and incidence and mortality rates are rapidly increasing in many previously …

Colon cancer has been associated with several nutrients and foods. The authors used data
from a population-based study conducted in Northern California, Utah, and Minnesota to …

Background & Aims: The concept of a CpG island methylator phenotype (CIMP), especially
in microsatellite stable colon cancer, is not accepted universally. We therefore evaluated a …

Some previous studies have reported an improved prognosis in sporadic colon cancers
with microsatellite instability, whereas others have not. In addition, relatively few of those …

Low levels of physical activity and high levels of energy intake and body mass have all
been directly associated with colon cancer. The purpose of this study was to determine how …

Objective. —The purpose of this study is to assess the impact of family history on the risk of
developing breast cancer. Design. —A case-control study design was used. Setting. —To …