Highly evolvable malaria vectors: The genomes of 16 Anopheles mosquitoes
…, V Stegniy, CJ Struchiner, GWC Thomas, M Tojo… - Science, 2015 - science.org
INTRODUCTION Control of mosquito vectors has historically proven to be an effective
means of eliminating malaria. Human malaria is transmitted only by mosquitoes in the genus …
means of eliminating malaria. Human malaria is transmitted only by mosquitoes in the genus …
Genome sequences of the human body louse and its primary endosymbiont provide insights into the permanent parasitic lifestyle
…, JT Reese, A Popadic, M Tojo… - Proceedings of the …, 2010 - National Acad Sciences
As an obligatory parasite of humans, the body louse (Pediculus humanus humanus) is an
important vector for human diseases, including epidemic typhus, relapsing fever, and trench …
important vector for human diseases, including epidemic typhus, relapsing fever, and trench …
[HTML][HTML] Genomic insights into the Ixodes scapularis tick vector of Lyme disease
…, MS Severo, N Silverman, L Šimo, M Tojo… - Nature …, 2016 - nature.com
Ticks transmit more pathogens to humans and animals than any other arthropod. We describe
the 2.1 Gbp nuclear genome of the tick, Ixodes scapularis (Say), which vectors pathogens …
the 2.1 Gbp nuclear genome of the tick, Ixodes scapularis (Say), which vectors pathogens …
Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes
Introduction The human genome is peppered with mobile repetitive elements called long
interspersed nuclear element–1 (L1) retrotransposons. Propagating through RNA and cDNA …
interspersed nuclear element–1 (L1) retrotransposons. Propagating through RNA and cDNA …
Genome of Rhodnius prolixus, an insect vector of Chagas disease, reveals unique adaptations to hematophagy and parasite infection
…, M Sterkel, ML Taracena, M Tojo… - Proceedings of the …, 2015 - National Acad Sciences
Rhodnius prolixus not only has served as a model organism for the study of insect physiology,
but also is a major vector of Chagas disease, an illness that affects approximately seven …
but also is a major vector of Chagas disease, an illness that affects approximately seven …
[HTML][HTML] Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition
About half of all cancers have somatic integrations of retrotransposons. Here, to characterize
their role in oncogenesis, we analyzed the patterns and mechanisms of somatic …
their role in oncogenesis, we analyzed the patterns and mechanisms of somatic …
[HTML][HTML] Genome analysis of a major urban malaria vector mosquito, Anopheles stephensi
…, G Maslen, C Oringanje, Y Qi, R Settlage, M Tojo… - Genome biology, 2014 - Springer
Background Anopheles stephensi is the key vector of malaria throughout the Indian subcontinent
and Middle East and an emerging model for molecular and genetic studies of mosquito-…
and Middle East and an emerging model for molecular and genetic studies of mosquito-…
[PDF][PDF] The L‐α‐Lysophosphatidylinositol/G Protein–Coupled Receptor 55 System Induces the Development of Nonalcoholic Steatosis and Steatohepatitis
…, B Porteiro, D Beiroa, C Folgueira, M Tojo… - …, 2021 - Wiley Online Library
Background and Aims G protein–coupled receptor (GPR) 55 is a putative cannabinoid
receptor, and l‐α‐lysophosphatidylinositol (LPI) is its only known endogenous ligand. Although …
receptor, and l‐α‐lysophosphatidylinositol (LPI) is its only known endogenous ligand. Although …
[HTML][HTML] GPR55: a new promising target for metabolism?
…, RJ Hernández-Bautista, M Tojo… - Journal of …, 2017 - jme.bioscientifica.com
GPR55 is a G-protein-coupled receptor (GPCR) that has been identified as a new cannabinoid
receptor. Given the wide localization of GPR55 in brain and peripheral tissues, this …
receptor. Given the wide localization of GPR55 in brain and peripheral tissues, this …
[HTML][HTML] Aberrant integration of Hepatitis B virus DNA promotes major restructuring of human hepatocellular carcinoma genome architecture
…, A Pequeño-Valtierra, J Zamora, M Tojo… - Nature …, 2021 - nature.com
Most cancers are characterized by the somatic acquisition of genomic rearrangements
during tumour evolution that eventually drive the oncogenesis. Here, using multiplatform …
during tumour evolution that eventually drive the oncogenesis. Here, using multiplatform …